摘要
目的观察冷针穿刺放液术后补肾祛瘀方合针刺治疗耐克罗米芬多囊卵巢综合征(PCOS)不孕症临床效果。方法 170例均为2011年3月—2013年10月收治耐克罗米芬PCOS不孕症患者,以随机区组法分为对照组(85例)和观察组(85例),分别采用单用冷针穿刺放液术和在此基础上术后加用补肾祛瘀方合针刺辅助治疗;观察治疗前后两组患者临床疗效;随访自发排卵率及妊娠率;检测治疗前后血清性激素及卵巢血流动力学指标水平。结果观察组妊娠成功(63例)显著优于对照组(52例),差异有统计学意义(χ2=7.63,P<0.05);观察组患者随访3、6个月的自发排卵率分别为75.29%、88.24%均明显高于对照组(56.47%、67.06%),差异有统计学意义(χ2分别为6.70,10.98;P<0.05);观察组总妊娠率为74.12%,高于对照组(61.18%),两组比较,差异亦有统计学意义(χ2=4.46,P<0.05);与治疗前比较,两组治疗后血清黄体生成素(LH)、睾酮(T)、雌激素(E2)水平均明显下降,卵泡刺激素(FSH)、收缩期血流峰值速度(PSV)、舒张末期容量(EDV)水平升高(P<0.05),观察组治疗后LH、T、E2水平下降幅度及FSH、PSV、EDV升高水平均大于对照组(P<0.05)。结论冷针穿刺放液术后补肾祛瘀方合针刺治疗耐克罗米芬PCOS不孕症可有效促进月经恢复,提高妊娠成功几率,且有助于改善性激素和卵巢血流灌注水平。
Objective To observe the clinical effects of Bushen Quyu Recipe（BQR） combined with acupuncture in treatment of clomiphene-resistant polycystic ovary syndrome（PCOS） infertility patients after cold needle puncture drainage operation.Methods Totally 170 clomiphene-resistant PCOS infertility patients were recruited from March 2011 to October 201 3,who were assigned to the control group and the observation group according to random blocking method,85 cases in each group.Patients in the control group received cold needle puncture drainage operation alone,while those in the observation group additionally took BQR and received acupuncture after cold needle puncture drainage operation.Clinical efficacy was observed in the two groups before and after treatment.The spontaneous ovulation rate and the pregnancy rate were followed-up.The levels of serum sex hormones and hemodynamic indicators of ovarian blood flow were detected in the two groups before and after treatment.Results Successful pregnancy occurred in 63 cases of the observation group,significantly better than that of the control group（52 cases;χ^2=7.63,P〈0.05）.The spontaneous ovulation rate was 75.29%at month 3 of follow-ups and 8 8.24%at month 6 of follow-ups in the observation group,significantly higher than those of the control group[56.47%,67.06%;χ^2=6.70,χ^2=10.98,P〈0.05）.In the observation group the total pregnancy rate was 74.12%,higher than that of the control group[61.18%;χ-2=4.46,P〈0.05）.Compared with before treatment in the same group,levels of luteinizing hormone（LH）,testesterone（T）,estradiol（E2） significantly decreased in the two groups after treatment;levels of follicular stimulating hormone（FSH）,peak systolic velocity（PSV）,end diastolic volume（EDV） obviously increased in the two groups after treatment（P〈0.05）.The decrement of T,LH,E2 levels and the increment of FSH,PSV,EDV levels were obviously higher in the observation group than in the control group（P〈0.05）.Conclusion BQR combined with a
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2016年第9期1038-1041,共4页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
手术
补肾祛瘀方
针刺
多囊卵巢综合征
不孕
operation
Bushen Quyu Recipe
acupuncture
polycystic ovary syndrome
infertility
