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两种胰岛素强化治疗方案治疗社区2型糖尿病疗效观察 被引量:6

Observation of curative effect by two intensive insulin therapies for community type 2 diabetes mellitus
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摘要 目的分析两种胰岛素强化治疗方案治疗社区2型糖尿病的疗效,为临床提供参考。方法 96例社区2型糖尿病患者,随机分为对照组与实验组,各48例。对照组采取诺和灵R联合诺和灵N注射治疗,实验组采取门冬胰岛素联合甘精胰岛素注射治疗。观察比较两组患者治疗后的空腹血糖、餐后2 h血糖、达标时间以及低血糖发生情况。结果实验组低血糖发生率及达标时间0、(7.63±1.21)d均优于对照组10.42%、(11.54±3.97)d,差异具有统计学意义(P<0.05);两组空腹血糖及餐后2 h血糖比较差异无统计学意义(P>0.05)。结论对社区2型糖尿病患者采取门冬胰岛素联合甘精胰岛素注射治疗,能够有效缩短患者的达标时间,降低患者发生低血糖的几率,降糖效果显著,值得推广。 Objective To analyze curative effect by two intensive insulin therapies for community type 2 diabetes mellitus, and to provide clinical reference. Methods A total of 96 community type 2 diabetes mellitus patients were randomly divided into control group and experimental group, with 48 cases in each group. The control group received Novolin R combined with Novolin N for injection, and the experimental group received insulin aspart combined with insulin glargine for injection. Observation and comparison were made on fasting blood glucose, 2 h postprandial blood glucose, standard time and hypoglycemia between the two groups after treatment. Results The experimental group had all better incidence of hypoglycemia as 0 and standard time as(7.63±1.21) d than 10.42% and(11.54±3.97) d in the control group, and the difference had statistical significance(P〈0.05), while there was no statistically significant difference of fasting blood glucose and 2 hpostprandial blood glucose between the two groups(P〈0.05). Conclusion Implement of insulin aspart combined with insulin glargine for injection in community type 2 diabetes mellitus patients can effectively shorten standard time, and reduce incidence of hypoglycemia. This method provides precise effect in reducing blood glucose, and it is worth promoting.
作者 张作良
出处 《中国现代药物应用》 2016年第14期5-7,共3页 Chinese Journal of Modern Drug Application
关键词 胰岛素强化治疗 社区2型糖尿病 疗效 Intensive insulin therapy Community type 2 diabetes mellitus Curative effect
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