摘要
目的:分析临床上针对2型糖尿病的患者,使用甘精胰岛素、二甲双胍、阿卡波糖联合治疗的效果和安全性。方法:选取2型糖尿病患者60例,经随机数字表法分组,A组20例使用甘精胰岛素联合二甲双胍治疗;B组20例使用甘精胰岛素联合阿卡波糖治疗;C组20例使用甘精胰岛素、二甲双胍、阿卡波糖联合治疗,对比3组治疗效果与安全性。结果:3组患者治疗后HbAlc、2hPBG、FBG均明显低于治疗前,且C组患者治疗后的HbAlc、2hPBG、FBG也明显低于A组、B组;胰岛素使用量明显少于A组、B组;血糖达标时间明显短于A组、B组(P<0.05);3组患者低血糖发生率比较差异无统计学意义(P>0.05)。结论:2型糖尿病患者使用甘精胰岛素、二甲双胍、阿卡波糖联合治疗效果显著,且安全性较高,能有效降低、控制血糖水平。
Objective:To analyze the clinical efficacy and safety of combined application of insulin glargine,metformin and acarbose to the treatment of type 2 diabetes.Methods:60 cases of patients with type 2 diabetes were selected and randomized two group.20 patients in Group A were administered with the combination of insulin glargine with metformin,20 patients in Group B were treated with insulin glargine combined with acarbose therapy,and another 20 patients in Group C received the combined treatment of insulin,metformin and acarbose.therapeutic effects and safety of the three groups were compared.Results:After treatment,HbAlc,2 h PBG and FBG of the three groups became significantly lower;HbAlc,2 h PBG and FBG of Group C were significantly lower than those of Group A and B;the amount of insulin used was significantly less than that of Group A and B,and the time of blood glucose reaching the standard was significantly shorter than that of Group A and B(P<0.05).There was no statistically significant difference in the incidence of hypoglycemia among the three groups(P>0.05).Conclusion:The combination therapy of insulin glargine,metformin and acarbose is effective and safe in patients with type 2 diabetes.It can effectively reduce the control of blood sugar levels.
作者
邱湘钰
张锦和
陈微
QIU Xiangyu;ZHANG Jinhe;CHEN Wei(Dept.of Endocrinology,the People’s Hospital of Chaozhou,Chaozhou 521000,China;Dept.of ICU,the People’s Hospital of Chaozhou,Chaozhou 521000,China)
出处
《华夏医学》
CAS
2020年第2期47-50,共4页
Acta Medicinae Sinica
