摘要
目的探究孕三烯酮联合腹腔镜下电凝治疗子宫内膜异位症的临床疗效。方法将2014年1月至2015年3月第四军医大学西京医院就诊的74例子宫内膜异位症患者按随机数字表法分为对照组和观察组,各37例。观察组采用孕三烯酮联合腹腔镜下电凝治疗,对照组采用腹腔镜下电凝治疗。比较两组患者的术中出血量、术后康复时间、术后住院时间、肛门排气时间及治疗前后生殖激素[雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)]水平、不良反应以及临床疗效。结果治疗后,观察组患者总有效率高于对照组[91.9%(34/37)比73.0%(27/37)],差异有统计学意义(P<0.05)。观察组术后的康复时间、术后住院时间、肛门的排气时间及术中出血量均少于对照组[(10.2±1.8)d比(28.2±4.3)d、(3.5±0.5)d比(8.3±2.2)d、(22±5)h比(33±5)h、(66±9)mL比(130±15)mL],差异有统计学意义(P<0.01)。治疗后,观察组患者E2、LH、FSH均低于对照组[(99±23)ng/L比(156±29)ng/L,(2.7±0.8)U/L比(3.9±1.2)U/L,(2.6±1.1)U/L比(3.8±1.4)U/L],差异有统计学意义(P<0.01)。观察组总不良反应发生率低于对照组[8.1%(3/37)比59.5%(22/37)],差异有统计学意义(P<0.05)。结论孕三烯酮联合腹腔镜下电凝治疗子宫内膜异位症,创伤小,恢复快,不良反应少,受孕率高,疗效确切,值得在临床上推广应用。
Objective To evaluate the clinical efficacy of gestrinone combined laparoscopic electrocoagulation for endometriosis. Methods Total of 74 endometriosis patients in Xijing Hospital, the Fourth Military Medical University from Jan. 2014 to Mar. 2015 were divided into a control group and an observation group according to the random number table method, 37 cases each. The observation group was treated with gestrinone combined ]aparoseopic electrocoagnlation ,while the control group was only treated with laparoscopic electrecoagulation. The amount of bleeding, postoperative recovery time, postoperative hospitalization time, anal exhaust time and reproductive hormone [ estradiol （ E2 ）, progesterone （ LH ）, follicle stimulating hormone（FSH） ] before and after treatment, adverse reactions and clinical efficacy of the two groups were compared. Results After treatment, the total efficacy of the observation group was higher than the control group [ 91.9% （34/37） vs 73.4% （27/37） ] ,the difference was statistically significant （ P 〈 0. 05 ）. Postoperative recovery time, postoperative hospital stay, anal exhaust time and bleeding volume of the observation group were less than the control group[（10.2 ±1.8） d vs （28.2 ±4.3） d,（3.5 ±0.5） d vs （8.3 ± 2. 2 ） d, （ 22 ± 5 ） h vs （ 33 ± 5 ） h, （ 66 ± 9 ） mL vs （ 130 ± 15 ） mL ], the differences were statistically signifieant（P 〈0. 01 ）. After treatment,the E2 ,LH,FSH of the observation group were lower than those of the control group[（99±23） ng/Lvs （156±29） ng/L, （2.7±0.8） U/Lvs （3.9 ±1.2） U/L,（2.6± 1.1 ） U/L vs （ 3.8 ± 1. 4 ） U/L ], the differences were statistically significant （ P 〈 0.01 ）. The total incidence of adverse reactions of the observation group was lower than the control group [ 8. 1% （ 3/37 ） vs 59.5% （22/37）] ,the difference was statistically significant（P 〈0.05）. Conclusion Gestrinone combined laparoscopic electrocoagnlation treatment of endometr
出处
《医学综述》
2016年第12期2483-2486,共4页
Medical Recapitulate
