摘要
目的探讨腹腔镜术后联合应用促性腺素释放激素类似物（GnRH—d）治疗子宫内膜异位症的临床疗效。方法将接受腹腔镜手术治疗后的子宫内膜异位症患者185例随机分为两组，观察组与对照组分别接受GnRH-α（93例）和孕三烯酮（92例）治疗，服药后随访24个月，比较两组术后盆腔症状改善、复发及妊娠情况。结果观察组治疗后盆腔症状改善率为87．1％、妊娠率为79．3％，高于对照组的70．7％、52．4％（x^2=7．517，4．059，均P〈0．05），观察组复发率为19．4％，低于对照组的34．8％（x2=5．581，P〈0．05）。结论腹腔镜术后联合使用GnRH-α．治疗子宫内膜异位症可有效改善患者的盆腔症状、减少复发和提高妊娠率。
Objective To study the clinical effect of GnRH-α in treatment of patients with endometriosis after laparoscope surgery. Methods 185 endometriosis patients who got laparoscope surgery were randomly divided into the observation group （ 93 cases） and the control group （ 92 cases ）, and took GnRH-a and gastrinone, respectively. After 24 months follow-up, the outcomes of pelvic cavity symptom improvement, recurrence and pregnancy were observed. Results After treatment, the pelvic cavity symptom improvement （ 87.1% ） and pregnancy rate （79.3%） in the observation group was higher than those of the control group （70.7%, 52.4% ） （X2 = 7. 517,4. 059, all P 〈 0. 05）, and the recurrence rate（ 19.4% ） in the observation group was lower than that of the control group（34.8% ） （ X2 = 5. 581, P 〈 0.05）. Conclusion The treatment of endometriosis with GnRH-α combined with laparoscope surgery could attain desirable effect. Compared with gastrinone, it could effectively improve pelvic cavity symptom, decrease recurrence and increase the rate of pregnancy.
出处
《中国基层医药》
CAS
2012年第4期495-496,共2页
Chinese Journal of Primary Medicine and Pharmacy
