摘要
目的探讨冠心病患者P波离散度(PWD)和P波最大宽度(Pmax)与左心室舒张功能的相关性。方法选取冠心病患者100例,应用12导联同步心电图仪测量PWD和Pmax,依据PWD分为:PWD≥40 ms组,PWD<40ms组;依据Pmax时限分为:Pmax≥110 ms组,Pmax<110 ms组。比较各组患者冠状动脉狭窄程度、E/A比值、舒张期减速时间(DT)、左房内径(LAD)、左心室舒张末期内径(LVEDD)、左心室射血分数(LVEF)、阵发性房颤发生率等指标。结果 PWD≥40 ms组及Pmax≥110 ms组的冠状动脉狭窄程度、E/A比值、DT、LAD、LVEDD及阵发性房颤发生率与对照组相比差异有统计学意义(P<0.05);所有患者的PWD及Pmax与冠状动脉狭窄程度、DT、LAD、LVEDD成正相关,与E/A比值呈负相关(P<0.05);多元线性回归显示在控制了年龄、房颤、高血压病、生化指标等因素后,上述指标与PWD及Pmax独立相关性仍较显著。结论 P波离散度和P波最大宽度能够在一定程度上反映冠心病患者左心室舒张功能及预测阵发性心房颤动的发生。
Aim To explore the correlation between P-wave dispersion（PWD） maximum P-wave duration（Pmax） and left ventricular diastolic function.Methods the paper measures PWD Pmax of 100 coronary artery disease patients with 12-lead ECG synchronization,who are grouped into greater than 40 ms and less than 40 ms according to PWD,and grouped into greater than 110 ms and less than 110 ms according to Pmax.Indices such as severity of coronary stenosis,E / A ratio,DT,LAD,LVEDD,LVEF,paroxysmal atrial fibrillation etc.are compared among groups as well.Results Group of PWD ≥40 ms and Pmax ≥110 ms have statistically significant differences from control groups in severity of coronary stenosis,E / A ratio,DT,LAD,LVEDD,paroxysmal atrial fibrillation（P〈0.05）.PWD Pmax of all patients are positively correlated with severity of coronary stenosis,DT,LAD,LVEDD,while negatively correlated with E / A ratio（P〈0.05）,too.Result of multi-regression also indicates that indices are independently correlated with PWD and Pmax significantly after controlling variables such as age,atrial fibrillation,hypertension,biochemical marker etc.Conclusion P-wave dispersion maximum P-wave duration can reflect left ventricular diastolic function and forecast paroxysmal atrial fibrillation（PAF） in some extent.
出处
《中国动脉硬化杂志》
CAS
北大核心
2015年第7期709-712,共4页
Chinese Journal of Arteriosclerosis
关键词
P波离散度
P波最大宽度
冠心病
左心室舒张功能
P wave dispersion
maximum P-wave duration
coronary artery disease
left ventricular diastolic function
