摘要
目的:了解国内慢性便秘疗效评价的现状.方法:以"便秘"为关键词检索2006-01/2015-07中国知网期刊全文数据库,统计纳入研究文献中使用的疗效评价方法,以及相关治疗方式、随访时间等.结果:检索共获得文献5610篇,依据标准筛选后共有370篇文献纳入研究.使用疗效评价方法情况包括:使用分级疗效判定法348篇(94.1%)、主要症状对比法82篇(21.6%)、症状总体积分法53篇(14.3%)、实验室检查对比法41篇(11.1%).上述疗效评价方法单独或结合使用;参照公认疗效判定标准或公认的评分标准文献202篇(53.6%),仅用自拟疗效判定标准或自拟症状积分标准文献168篇(45.4%),但逐年下降;纳入文献中涉及随访方法评价疗效83篇(22%).使用基于患者临床报告结局(Patient Reported Outcomes,PRO)方法的文献4篇(1.1%).结论:国内慢性便秘的疗效评价中,常用疗效评价方法多使用自拟疗效判定标准和自拟症状积分,文献随访率低.需要重视使用基于PRO评价疗效.
AIM：To summarize the current status of efficacy evaluation in chronic constipation in China.METHODS：Using ＂constipation＂ as a key word,the papers published between 2006 and 2015 in the CNKI full text database index system were searched.The methods of efficacy evaluation,therapeutic method and follow-up duration were analyzed.RESULTS：A total of 370 papers were identified from 5610 papers selected.There were four methods of efficacy evaluation：classification assessment in 348（94.1%） papers（94.1%）,main symptom comparison in 82（21.6%）,clinical symptom scoring in 53（14.3%）,and laboratory result comparison in 41（11.1%）.These methods were used separately or in combination.168（45.4%） papers used the selfmade clinical efficacy evaluation standard or the self-made symptom scoring questionnaire only.83（22%） papers papers involved the follow-up.Only 4 papers used the Patient Reported Outcomes（PRO）.CONCLUSION：Now in China,the methodologies of efficacy evaluation in chronic constipation vary greatly.Self-made clinical efficacy evaluation standards or the self-made integral questionnaires are widely used.Follow-up rate is low.PRO use should be strengthened in later clinical practice.
出处
《世界华人消化杂志》
CAS
2015年第34期5566-5572,共7页
World Chinese Journal of Digestology
基金
南京市重大公共卫生专项"排便功能障碍性疾病系列诊治技术的研究和推广"基金资助项目
No.2100409~~
关键词
慢性便秘
疗效
评价方法
患者报告临床结局
症状
随访
Chronic constipation
Methodology
Efficacy evaluation
Patient reported outcomes
Symptoms
Follow-up
