摘要
目的:评估MR扩散加权成像(DWI)对子宫腺肌病高强度聚焦超声(HIFU)治疗后早期疗效评价的价值。方法:55例患者依据病灶范围,分为局灶性44例,弥漫性11例。在HIFU术前及消融后5 d内行DWI、CE-MRI检查,分析病灶的DWI信号特征,并计算不同区域表观弥散系数(ADC)差异。结果:55例DWI均能明确残留病灶及消融灶范围;HIFU术前病灶平均ADC值为(1.36±0.21)×10-2 mm2/s,术后5 d残留灶平均ADC值为(1.49±0.23)×10-2 mm2/s,较术前升高,两者经t检验,t=3.10,P=0.003,两者间差异有统计学意义,术后5 d消融灶平均ADC值为(1.22±0.24)×10-2 mm2/s,较术前降低,残留灶与消融灶间差异经t检验,t=6.02,P=0.000,两者间差异亦有统计学意义(P<0.005)。结论:DWI及ADC值是评价子宫腺肌病HIFU术后早期消融效果非常有效的方法。
Objective： To retrospectively analyze the early-term value of diffusion weighted imaging （DWI） features of ade- nomyosis after high intensity focused ultrasound（HIFU） ablation. Methods： Fifty-five patients（44 cases of focal uterine adeno- myosis, 11 cases of diffuse uterine adenomyosis） underwent HIFU ablation, DWI and CE-MRI was performed one week before and 5 days after HIFU. The feature of DWI signal and ADC value of the residual part of adenomyosis was analyzed, and then calculated the difference of ADC values among different areas. Results： The residual part of adenomyosis was found in DWI. The signal intensity of the residual part of adenomyosis in DWI sequence increased at 5 days after HIFU ablation. The ADC value of the residual part of adenomyosis was （1.49±0.23）×10^-2 mm^2/s at 5 days after HIFU ablation, was higher than the ADC value （（1.36±0.21）×10^-2 mm^2/s） before operation, and the t value of T-test was 3.10, the value of P is 0.003, there was significant difference between before and after surgery. And the ADC value of the focal ablation part of adenomyosis was （1.22±0.24）×10^-2 mm^2/s when was HIFU ablation after 5 days, was lower than the ADC value （（1.36±0.21）×10^-2 mmZ/s） before operation. The t value of T-test was 6.02, the value of P is 0.000, the significant difference was found between the ADC val- ue of the residual part and focal ablation part（P〈0.005）. Conclusion： DWI and ADC value are vepy useful means for monitoring the early term effectiveness of ablation of adenomyosis after HIFU ablation.
出处
《中国临床医学影像杂志》
CAS
北大核心
2015年第11期804-807,共4页
Journal of China Clinic Medical Imaging
关键词
子宫疾病
磁共振成像
超声疗法
Uterine diseases
Magnetic resonance imaging
Ultrasonic therapy
