摘要
目的比较医院重症监护病房(ICU)与普通病房患者感染的阴沟肠杆菌的耐药性,为临床合理应用抗生素提供科学依据。方法通过临床病原学标本检测和药敏试验方法,对某教学医院临床送检病原学标本检测结果进行比较分析。结果该医院在2011年12月-2014年4月,从临床送检标本中共分离出阴沟肠杆菌197株,ICU占16.75%,临床普通科室占83.25%。197株阴沟杆菌中有68.52%分离自病人的痰标本,其次为感染切口分泌物和外伤伤口分泌物,构成比分别7.61%和5.58%,分居2、3位。ICU患者标本中分离出的阴沟肠杆菌对临床常用抗菌药物的耐药率明显高于其他普通临床科室患者标本分离者,且耐药谱不同。结论该医院ICU患者标本分离的阴沟肠杆菌对抗菌药物耐药率明显高于非ICU患者分离者,应当加强耐药菌监测和药敏试验,严格管控抗菌药物使用。
Objective To study the hospital intensive care unit（ ICU）and ordinary ward infection of patients with drug re-sistance of Enterobacter cloacae,provide scientific basis for clinical rational use of antibiotics. Methods Clinical patho-genic bacteria detection and drug sensitivity test method were used to compare and analyze clinical laboratory pathogenic samples of a teaching hospital. Results From December 2011 to April 2014, 197 strains of E. cloacae were isolated from clinical samples,16. 75% came from ICU,83. 25% came from the clinical common department. Of E. cloacae, 68. 52% were from sputum specimens,followed by incisional wound secretions（7. 61%）and wound secretions,（5. 58%）. The resistance rate of E. cloacae isolated from ICU was significantly higher than that from other common clinical departments,and the drug resistance spectrum was different. Conclusion The resistance rate of E. cloacae isolated from ICU was significantly higher than that from other common clinical departments. We should strengthen the monitoring of drug resistant pathogens and drug sensitivity test, control the use of antimicrobial drugs strictly.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第8期788-790,794,共4页
Chinese Journal of Disinfection
基金
贵州省黔南州社会发展科技项目(黔南科合社字[2013]20号)
关键词
重症监护病房
阴沟肠杆菌
抗菌药物
耐药性
intensive care unit
Enterobacter cloacae
antibiotics
drug resistance
