摘要
目的了解某医院分离的1 508株非发酵菌种类分布及其耐药性,为合理选用抗菌药物提供依据。方法采用回顾性调查方法,对某医院临床分离的非发酵菌分布情况进行统计分析。结果该医院从住院患者送检标本中共分离出非发酵菌1 508株,铜绿假单胞菌720株,占47.7%;鲍曼不动杆菌287株,占19.0%;嗜麦芽窄食单胞菌103株,占6.8%。非发酵菌分离标本来源痰液占48.6%,灌洗液占19.8%。临床分离的非发酵菌普遍耐药,以嗜麦芽窄食单胞菌耐药情况最严重,对所试验的13种抗菌药物中的10种耐药率都达到100%;铜绿假单胞菌对复方新诺明和氯霉素全部耐药。结论该医院临床分离非发酵菌以铜绿假单胞菌为主,应加强监测;非发酵菌耐药严重,呈现多重耐药趋势,应严格管控临床抗菌药物的使用。
Objective To investigate the distribution and drug resistance of 1 508 strains of non-fermentive bacteria isolated from some hospital,so as to provide reference for clinical rational use of antimicrobial drugs.Methods By means of the retrospective survey,the distribution of 1 508 strains of non-fermentive bacteria in a hospital were analyzed statistically.Results A total of 1 508 strains of non-fermentive bacteria were isolated,including 720（ 47.7%） strains of Pseudomonas aeruginose,287（ 19.0%） strains of Acinetobacter baumannii,103（ 6.8%） strains of Stenotrophomonas maltophilia.Non-fermentive specimens were mainly isolated from sputum,accounting for 48.6% and lavage fluid accounted for 19.8%.The clinical isolates of non-fermentive were generally resistant to antibiotics,and the drug resistance of Acinetobacter baumannii was the most serious,the antimicrobial drug resistance rates of 10 among 13 strains reached 100%; All Pseudomonas aeruginosa was resistant to compound Sulfamethoxazole and Chloramphenicol.Conclusion The clinical isolates of non-fermentive bacteria in the hospital are dominated by Pseudomonas aeruginosa,suggesting that the monitoring should be strengthened.The drug resistance of non-fermentive bacteria is serious,and many strains show multiple drug resistance.The use of clinical antibiotics should be strictly controlled.
出处
《中国消毒学杂志》
CAS
北大核心
2016年第4期332-334,共3页
Chinese Journal of Disinfection
基金
中华医院感染控制研究基金(ZHYG2014-0007)
关键词
非发酵菌
耐药性
医院感染
监测
non-fermentive bacteria
drug resistance
nosocomial infection
monitoring
