摘要
目的：分析比较莫西沙星、阿奇霉素、米诺环素3种临床上常用来治疗女性生殖道沙眼衣原体感染的抗生素临床疗效以及治疗效果随年限的变迁,并比较它们的优劣。方法：收集2011~2014年蚌埠医学院第一附属医院皮肤性病科女性生殖道沙眼衣原体感染患者完整临床病历,分析汇总抗生素应用及疗效情况。结果：莫西沙星治疗沙眼衣原体感染疗效优于阿奇霉素与米诺环素,而阿奇霉素与米诺环素之间疗效无差异;2013~2014年阿奇霉素治愈率较2011年下降,差异有统计学意义（P〈0.05）,各年度莫西沙星及米诺环素治愈率差异无统计学意义（P〉0.05）。结论：泌尿生殖道沙眼衣原体感染推荐应用莫西沙星或米诺环素治疗,治愈率高且疗效稳定。
Objective： To analyze and compare the therapeutic effects of moxifloxacin,azithromycin,and minocycline in treatment of female genital tract Chlamydi trachomatis（ Ct） infection and the changes of therapeutic effects with time,compare the advantages and disadvantages. Methods： The intact clinical records of the patients with genial tract Ct infection in Department of Dermatology STD in the hospital from 2011 to 2014 were collected,the usage and therapeutic effect were analyzed and collected. Results： The curative effect of moxifloxacin was better than those of azithromycin and minocycline,but there was no significant difference in the curative effect between azithromycin and minocycline; the curative rate of azithromycin in 2013 and 2014 was statistically significantly lower than those in 2011（ P〈0. 05）,there was no statistically significant difference in the annual curative rate between minocycline and moxifloxacin（ P〉0. 05）. Conclusion： Minocycline or moxifloxacin are recommended to treat genial tract Ct infection,the curative rate is high and the curative effect is stable.
出处
《中国妇幼保健》
CAS
2015年第18期3019-3021,共3页
Maternal and Child Health Care of China
