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雌激素对视网膜主要细胞功能的影响 被引量:1

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摘要 雌激素通过与雌激素受体(ER)结合而发挥生理功能,ER亚型和特异性激动剂和拮抗剂的研究进展为进一步认识雌激素作用机制提供了可能.雌激素可能通过对视网膜血管内皮细胞、色素上皮细胞、神经节细胞、光感受器细胞和Müller细胞等主要视网膜细胞功能的影响,改善血视网膜屏障、保护视网膜光感受器细胞、视神经,减轻氧化应激反应对视网膜色素上皮细胞损害.详尽研究ER各亚型在视网膜主要细胞的分布及特异性激动剂和拮抗剂对这些细胞的作用将为眼底病的防治开拓一个新的领域.
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2015年第3期314-317,共4页 Chinese Journal of Ocular Fundus Diseases
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参考文献60

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