摘要
目的:对比研究阴道镜活检与人乳头瘤病毒检测在宫颈病变诊断中的临床价值。方法:选取我院2012年1月至2014年3月接受宫颈病变筛查的2560例已婚妇女为研究对象,对其先行人乳头瘤病毒(HPV)检测,再做阴道镜活检,对比两次检测结果,进行统计学分析,并以病理组织学检测结果作为金标准,判断两种检测方案灵敏度、特异性及准确率。结果:HPV检测阳性343例,阴道镜活检阳性527例,两组比较,差异具备统计学意义(P<0.05);金标准对比显示,HPV检测灵敏度、特异性、准确率,阴道镜活检灵敏度、特异性、准确率,两组比较,差异具备统计学意义(P<0.05)。结论:阴道镜活检与HPV检测均对宫颈病变诊断具有一定的价值,在单独应用的情况下,阴道镜活检具有更好的检出效果,但考虑到保证检测准确率,宜将两者联合应用。结论:阴道镜活检与HPV检测在宫颈病变诊断中均有良好效果,根据具体情况选择合适的检测方式。
Objectives： To comparatively study the clinical diagnostic value of colposcopy biopsy and human papilloma virus detection in the diagnosis of cervical lesions. Methods： 2560 married women in our hospital between January 2012 and March 2012 for cervical lesion screening were selected as the research objects. All objects received human papilloma virus（ HPV） detection and colposcopy biopsy accordingly. The test results were compared and statistically analyzed. Using the histologic results as the gold standard,the detection sensitivity,specificity and accuracy of the two methods were determined. Result： 343 cases and 527 cases were test positive for HPV and colposcopy biopsy respectively,with statistically significant difference（ P〈0. 05）; Compared with gold standard,the difference in sensitivity,specificity,accuracy between HPV detection and colposcopy biopsy were statistically significant（ P〈0. 05）. Conclusion： Colposcopy biopsy and HPV detection both have certain value in cervical disease diagnosis. In the case of single application,colposcopy biopsy has better detection effect,but considering the detection accuracy,appropriate joint application of both should be adopted. Conclusion： Colposcopy biopsy and HPV detection all have good results in the diagnosis of cervical lesions,and appropriate methods should be considered according to the specific situation.
出处
《中国性科学》
2015年第1期70-72,共3页
Chinese Journal of Human Sexuality
关键词
阴道镜活检
人乳头瘤病毒检测
宫颈病变
诊断价值
Colposcopy biopsy
Human papilloma virus detection
Cervical lesions
Diagnostic value
