摘要
目的：探讨中青年男性勃起功能障碍（erectile dysfunction,ED）与代谢综合征（metabolic syndrome,MS）及睾酮水平的相关性。方法：2012年2月至2014年1月,调查门诊154例20~59岁男性器质性ED患者与103例性生活正常男性的一般情况、腰围、血压、空腹血糖、总甘油三酯、高密度脂蛋白、血清总睾酮、国际勃起功能评分5项以及勃起功能指标,比较ED组与非ED组,以及ED患者中MS者与非MS者各项指标差别。结果：中青年ED组MS患病率显著高于非ED组MS患病率（P〈0.05）,ED组与非ED组腹围、血压、腹围、空腹血糖、高密度脂蛋白及总睾酮均有有显著性差异（P〈0.05）。ED组中MS者与非MS者勃起功能各项指标及总睾酮有显著性差异（P〈0.05）。多元logistic回归分析MS各项指标及总睾酮与ED相关性分析,发现腰围与ED密切相关（P〈0.01）。结论：中青年ED患者并发MS患病率较正常人群明显增高,ED患者中并发MS者睾酮水平较低、勃起功能较差。中心性肥胖与中青年ED密切相关。
Objective： To investigate the association of erectile dysfunction（ ED） with metabolic syndrome（ MS） and the total testosterone（ t T） level in young and middle-aged men. Methods： This study included 154 organic ED outpatients aged 20- 59 years and 103 age-matched men with normal sexual life. We obtained their waist circumference（ WC）,blood pressure（ BP）,fasting blood glucose（ FBG）,triglyceride（ TG）,high density lipoprotein（ HDL）,t T,IIEF-5 score,erectile function indexes and other relevant variables,and compared them between the ED and non-ED groups as well as between the ED patients with MS and those without MS.Results： The prevalence of MS was significantly higher in the ED patients than in the non-ED males（ 40. 9 vs 17. 4%,P〈0. 01）.Statistically significant differences were found between the ED and non-ED groups in WC（ [90. 80 ± 4. 90]vs [87. 70 ± 4. 60]cm,P〈0. 01）,SBP（ [134. 40 ± 14. 40] vs [129. 90 ± 12. 40] mm Hg,P〈0. 05）,DBP（ [86. 20 ± 7. 80] vs [83. 60 ± 8. 60] mm Hg,P〈0. 05）,FBG（ [5. 48 ± 1. 02] vs [5. 11 ± 0. 91] mmol / L,P〈0. 01）,HDL（ [1. 12 ± 0. 27] vs [1. 26 ± 0. 29] mmol / L,P〈0. 01）,and t T（ [15. 98 ± 6. 55]vs [17. 95 ± 7. 39]nmol / L,P〈0. 05）,as well as between the ED patients with MS and those without MS in such erectile function indexes as t T（ [14. 49 ± 6. 23]vs [17. 01 ± 6. 60]nmol / L,P〈0. 05）,erectile penile circumference（ [9. 67 ± 1. 09]vs [10. 16 ± 1. 01]cm,P〈0. 01）,erectile penile length（ [10. 40 ± 1. 20]vs [10. 79 ± 1. 07]cm,P〈0. 05）,glans temperature（ [31. 33 ± 0. 65] vs [31. 80 ± 0. 82] ℃,P〈0. 01）,and mean axial hardness of the penis（ [332. 60 ± 137. 90]vs [419. 20 ± 145. 80]g,P〈0. 01）. WC was significantly correlated with the incidence of ED（ P〈0. 01）. Conclusion： The prevalence of MS is significantly higher in young and middle-aged ED patients than in normal males,and MS is associated with a lower testosterone level and poorer erectile performan
出处
《中华男科学杂志》
CAS
CSCD
2014年第11期999-1003,共5页
National Journal of Andrology
关键词
勃起功能障碍
代谢综合征
睾酮
中心性肥胖
中青年男性
erectile dysfunction
metabolic syndrome
testosterone
central obesity
young and middle-aged men
