摘要
目的研究慢性乙型肝炎青年患者的器质性勃起功能障碍(ED)和代谢综合征(MS)之间的关系,探讨影响慢性乙肝青年男性患者器质性ED患者代谢综合征的主要危险因素。方法收集121例慢性乙肝青年男性患者,对所有患者进行数据记录统计及国际勃起功能5项评分(IIEF-5),并参照MS诊断标准将患者分为ED组和非ED组,对比两组患有MS比例,并对两组病患的年龄等临床指标进行对比并分析两组之间的差异,按照IIEF-5项评分对所有ED病患进行病情严重程度分级,对MS组与非MS组患者病情严重程度进行对比,结合MS危险因素与IIEF-5评分,进一步去评估MS危险因素与IIEF-5评分两者之间是否具有相关性。结果在所有慢性乙型肝炎患者中,ED组内患有MS 47例,占ED组患者77.0%;非ED组内患有MS 28例,占非ED组患者46.7%;ED组内患有MS的比例显著高于非ED组内患有MS比例(P<0.05)。ED组患者体重、体重指数(BMI)、腰围明显高于非ED组(P<0.05),ED组患者总胆固醇、甘油三脂、低密度脂蛋白水平高于非ED组(P<0.05),而高密度脂蛋白水平显著低于非ED组患者(P<0.05),年龄、身高等其他指标两组差异无统计学意义(P>0.05)。无MS危险因素组IIEF-5评分显著高于伴有2个以上MS危险因素组患者(P<0.05),并且随MS危险因素数量逐步增加,IIEF-5评分逐渐下降。结论慢性乙型肝炎青年男性器质性ED患者较非ED患者MS患病率显著增高,中心性肥胖、高脂血症可能是构成慢性乙型肝炎青年男性患者器质性ED的主要危险因素。
Objective To investigate the relationship between dysfunction of erectile and metabolic syndrome of young men with chronic hepatitis, and find the main risk factors of erectile dysfunction in patients with metabolic syndrome. Methods 121 cases of chronic hepatitis B were enrolled. The general situation, physical examination, lipid metabolism, fasting blood glucose and the erectile function evaluated based on the international standard were analyzed. The diagnostic criteria for MS were set according to the International Diabetes Federation standard. The patients with MS were divided into ED group and non ED group. The rate of MS patients with ED were compared with non ED patients, and the index such as age, height and weight of patients with ED were compared with the non ED group. The patients with IIEF-5 were divided into MS group and non ED group. According to the IIEF-5 score, the severity of disease was graded in all patients with ED, and the severity of illness in patients with MS was compared with that of non MS group , and the risk factors of MS were combined with IIEF-5 score, and the correlation between IIEF-5 score and MS score was further evaluated. Results In chronic hepatitis B patients, there were 47 （77.0%） patients with MS in the ED group, and 28 （46.7%） in the non ED group;the rate of patients with MS were significantly higher than that in the non ED group （P〈0.05）. The body weight, body mass index （BMI）, waist circumference and waist circumference were significantly higher in ED group （P〈0.05）; total cholesterol, glycerol three fat and low density lipoprotein in ED group were higher than those in non ED group （P〈0.05）, and high density lipoprotein level in the ED group was significantly lower than that in non ED group （P〈0.05）, while the other index of the two groups had no significant differences （P〉0.05）. MS score in no IIEF-5 risk factor group was significantly higher than that with more than 2 MS risk factor group （P〈0.05）, and with the increase
出处
《热带医学杂志》
CAS
2016年第10期1299-1302,共4页
Journal of Tropical Medicine
