摘要
[目的]分析膝、髋关节骨性关节炎（osteoarthritis,OA）人工关节置换术后下肢深静脉血栓（deep venous thrombosis,DVT）形成的常见危险因素。[方法]2010年8月~2012年2月行全膝、髋关节置换术的患者456例,所有患者均在术后3~5 d行下肢深静脉造影。根据造影结果分为DVT组（男22例,女121例;平均年龄66.97岁）和非DVT组（男68例,女245例;平均年龄65.93岁）,分析两组患者中年龄、性别、糖尿病、高血压、心血管疾病史、血栓史、恶性肿瘤史、体重指数（Body mass index,BMI）、吸烟史及手术类型与DVT发生风险的潜在相关性。[结果]OA患者中,BMI≥25 kg/m2（OR=1.716;95%CI=1.100-2.675;P=0.017）和心血管疾病史（OR=3.403;95%CI=1.129-10.260;P=0.030）能显著增加关节置换术后DVT的发生风险。[结论]高BMI和心血管疾病史是膝、髋OA患者行关节置换术后DVT发生的危险因素。
[ Objective] To analyze the common risk factors of deep venous thrombosis （DVT） after joint arthroplasty due to knee or hip osteoarthritis （OA） . [ Methods] From August 2010 to February 2012, 456 patients who had undergone total knee or hip joint arthroplasty underwent venography of lower - extremity deep vein on postoperative days 3 to 5. Based on the re- sults of angiography, patients were divided into DVT group （22 males and 121 females, mean age 66. 97 years） and non - DVT group （68 males and 245 females, mean age 65.93 years） . The potential associations of DVT risk and age, gender, diabetes, hypertension, history of cardiovascular disease, VTE history, history of malignancy , body mass index （BMI） , smoking histo- ry, and types of surgery were analysed. [ Results] In OA patients, a BMI value of or more than 25 kg/m2 （OR = 1. 716; 95% CI = 1. 100 - 2. 675 ; P = 0. 017 ） and cardiovascular disease history （ OR = 3. 403 ; 95% CI = 1. 129 - 10. 260; P = O. 030） significantly increased DVT risk after joint arthroplasty. [ Conclusion] A higher BMI value and cardiovascular disease history are risk factors of DVT following joint arthroplasty in patients with knee or hip OA.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2014年第21期1939-1942,共4页
Orthopedic Journal of China
基金
国家杰出青年科学基金(项目批准号:No.81125013)
