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比索洛尔联合瑞舒伐他汀对老年冠心病心绞痛患者血清NT-proBNP、CK-MB水平的影响 被引量:7

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摘要 目的:探究比索洛尔联合瑞舒伐他汀对老年冠心病心绞痛患者血清N末端脑肽前体(NT-proBNP)、肌酸激酶同工酶(CK-MB)水平的影响。方法:选取2015年7月~2017年11月我院78例老年冠心病心绞痛患者,以随机数表法分组,各39例。对照组给予瑞舒伐他汀,实验组给予瑞舒伐他汀+比索洛尔,共治疗1个月。观察两组治疗效果、不良反应及血清CK-MB、NT-proBNP水平。结果:实验组治疗总有效率为92.31%,高于对照组(71.79%,P<0.05);与对照组比较,治疗后实验组血清CK-MB、NT-proBNP水平较低(P<0.05);实验组头晕、头痛等不良反应发生率与对照组比较,无显著差异(P>0.05)。结论:老年冠心病心绞痛采用比索洛尔联合瑞舒伐他汀治疗,可降低血清NT-proBNP、CK-MB水平,提高治疗效果,且安全性较高。
作者 张卫庆
出处 《北方药学》 2019年第1期140-141,共2页 Journal of North Pharmacy
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