摘要
目的 研究放射性核素骨显像对强直性脊柱炎 (AS)早期诊断的价值。方法 早期与可疑AS患者和对照组均行全身、局部及断层骨显像 ,测定骶髂关节 骶骨 (SI S)的放射性比值。结果早期与可疑AS患者的SI S比值分别为 1.5 3± 0 .11和 1.5 7± 0 .10 ,与对照组 (1.2 1± 0 .10 )比较 ,差异均有显著性 (t分别为 11.9和 15 .0 ,P均 <0 .0 1)。全身骨显像显示的 5例AS患者腰椎及外周关节的病变X线平片均未能发现 ;AS患者椎骨断层显像可准确判断病变位置 ,还可发现平面显像不能显示或可疑的椎骨异常浓聚灶。结论 放射性核素骨显像测定SI S比值发现早期AS较X线平片灵敏 ;全身骨显像及断层显像对了解AS病变部位有明显优势。
Objective To study the early diagnosis value of radionuclide bone imaging on ankylosing spondylitis (AS). Methods Patients with early and questionable AS and control subjects underwent 99Tcm-methylene diphosphonate (MDP) whole-body,local and SPECT bone imaging, and the sacroiliac joint/sacrum (SI/S) ratios were determined. Results The SI/S ratios of patients with early and questionable AS were 1.53±0.11 and 1.57±0.10, respectively, significantly higher compared with that of control group (1.21±0.10, P <0.01). Whole-body bone imaging showed the lesions in lumbar vertebrae and other joints of 5 patients with AS but that were not found in plain films. Vertebrae SPECT could correctly show lesion location of patients with AS and vertebra lesion which were not found or indeterminate in plain imaging. Conclusions The SI/S ratios determined with radionuclide bone imaging are more sensitive than plain film for diagnosing patients with early AS. Whole-body and SPECT bone imaging are obviously superior to plain imaging in observation of the lesions of different bone joints.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2001年第6期339-340,I002,共3页
Chinese Journal of Nuclear Medicine
