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骨显像和血HLA-B_(27)检测早期诊断强直性脊椎炎 被引量:5

A new method to ankylosing spondylitis diagnosis
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摘要 目的 探讨放射性核素骨显像及人类白细胞抗原 (HLA B2 7)检查对强直性脊椎炎 (AS)早期诊断价值。方法 对首次发病且X线检查未见异常的 35例后臀部疼痛患者作了骨显像及HLA B2 7测定 ,并制订了对AS的早期诊断标准 ,对患者临床随访 0 5~ 2 5a ,用纽约会议标准再次进行诊断 ,以评价早期诊断标准的准确性。结果 根据早期诊断标准有 30例患者被诊断为AS ,随访后再次诊断 ,其中 2 9例被诊断为AS ,前后 2次诊断符合率为 96 7%。结论 放射性核素骨显像与HLA B2 7检查相结合对AS的早期诊断和治疗可提供可靠依据。 Objective Discussing the value of radionuclide bone imaging and HLA B 27 detection for early ankylosing spondylitis (AS) diagnosis Methods Thirty five patients with newly started buttock pain and without abnormal X ray findings were given radionuclide bone imaging and HLA B 27 detection to make a primary diagnosis, and followed up for 0 5~2 5 years. A second diagnosis according to the New York Conference Standard was made Results There were 30 patients who were diagnosed with AS at the first work up, and 29 of them were confirmed as with AS according to New York Conference Standard after followed up , the first and second diagnosis coincidence rate was 96 7% Conclusions Radionuclide bone imaging combined with HLA B 27 antigen detection is of a very high value for early diagnosis of AS and can provide a reliable basis for early treatment
出处 《中华核医学杂志》 CAS CSCD 北大核心 2000年第6期257-258,共2页 Chinese Journal of Nuclear Medicine
关键词 强直性脊柱炎 放射性核素显像 HLA-B27抗原 Spondylitis, ankylosing Radionuclide imaging HLA B 27 antigen
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