摘要
目的 :评价HLA B2 7检测在强直性脊柱炎 (AS)临床诊断中的作用。方法 :对怀疑患有AS及其相关疾病的 12 0人作HLA B2 7检测 ,采用纽约标准改良的AS诊断标准作为本研究的AS诊断标准。结果 :本组受检 12 0例中 ,HLA B2 7(+)5 6例 ,占受检总数的 4 6 .6 7% ,按本研究改良标准诊断为AS 5 3例 ,其中HLA B2 7(+) 4 8例。本组 16周岁以下 13例受检者 ,HLA B2 7(+) 7例均符合JAS诊断标准。结论 :HLA B2 7检测对提高AS的诊断率和对轻型。
Objective: To evaluate the effect of HLA B27 detection in the diagnosis of ankylosing spondylitis (AS). Methods: HLA B27 detection was conducted in 120 people who were suspected of suffering from AS or related diseases. A modified diagnostic criteria, based on the New York criteria was used in the diagnosis of AS. Results: Among 120 people detected, 56 people (46.67%) were found to be HLA B27 positive and 53 people were diagnosed as having AS according to the modified diagnostic criteria. Of these 53 patients, 48 were HLA B27 positive. HLA B27 positive in 7 of 13 persons under 16 years old were found. All the 7 cases coincided with the diagnostic criteria of juvenile AS. Conclusion: It is suggested that the detection of HLA B27 is of value in discovering patients at early stage or in mild cases and might be helpful in enhancing the diagnostic accordance rate.
出处
《海军医学杂志》
2002年第3期218-220,共3页
Journal of Navy Medicine
