摘要
目的 探讨欣母沛预防高危剖宫产后出血的临床疗效.方法 选择江阴市人民医院2012年1 ～12月合并前置胎盘、羊水过多、巨大儿、双胎妊娠、子宫肌瘤等有产后出血倾向的孕妇120例,分为观察组60例和对照组60例.对照组在胎儿娩出后宫体注射缩宫素20 U、静脉滴注缩宫素20 U.观察组在上述治疗基础上,同时宫体注射欣母沛250 μg.比较两组产后2 h、24 h内的出血量及产后出血发生率.结果 观察组产后2 h、24 h内的出血量显著小于对照组[（240.36±37.43） mL vs （332.52±48.56） mL;（312.34±46.56） mL vs （404.54±57.74） mL]（P〈0.05）.观察组产后出血发生率显著低于对照组（6.67% vs 26.67%）（P〈0.05）.结论 预防性使用欣母沛能有效减少高危剖宫产术中术后出血量,降低产后出血发生率,从而降低围手术期并发症.
Objective To investigate the curative effects of hemabate on preventing postpartum hemor- rhage after Cesarean section with high risk factors. Methods A total of 120 patients with hemorrhage possi- bility due to Cesarean section with placenta previa, polyhydramnios, macrosomia, twin pregnancy, uterine myoma were selected and randomly divided into observation group and control group, with 60 case in each group. Control group was given oxytocin 20 U into their uterine corpus by injection and oxytocin 20 U by intravenous drip after fetal childbirth. Observation group was injected hemabate 250μg into the uterus on the basis of the treatment of control group. The 2 hours and 24 hours bleeding amounts after operation and the incidence of postpartum hemorrhage of the two groups were compared. Results The 2 hours and 24 hours bleeding amounts of the observation group were significantly less than the control group [ （240.36 ±37.43） mL vs （ 332.52 ±48.56 ） mL ; （ 312.34 ±46.56 ） mL vs （ 404.54 ±57.74 ） mL ] （ P 〈 0.05 ）, the incidence of postpartum hemorrhage was obviously lower than that in the control group（ 6.67% vs 26.67% ） （ P 〈 0.05 ）. Conclusion Preventive use of hemabate can effectively reduce the intraoperative blood loss,lower the post- partum hemorrhage incidence,thus reduce perioperative complications.
出处
《医学综述》
2014年第5期921-922,共2页
Medical Recapitulate
关键词
剖宫产
产后出血
欣母沛
Cesarean section
Postpartum hemorrhage
Hemabate
