摘要
目的观察欣母沛防治高危剖宫产孕妇产后出血的临床疗效。方法从2009年10月～2012年6月期间我院收治的分娩过程中有可能引起宫缩乏力高危因素而行剖宫产术的孕妇中选取150例，将其随机分为观察组（75例）和对照组（75例），观察组在胎儿娩出后立即向子宫体注射欣母沛250μg，对照组在胎儿娩出后向宫体内注射缩宫素20U，再静脉滴注缩宫素20u，观察对比两组产妇用药后的临床疗效，记录术后2h出血量及24h出血量以及不良反应情况。结果用药后观察组的总有效率为93．3％（70／75），显著高于对照组的74．7％（56／75），差异有统计学意义（P〈0．05）；观察组术后2h及24h出血量分别为（185．5±45．4）mL和（302．5±56．3）mL，显著少于对照组的（287．5±55．7）mL和（403．8±64．2）mL，差异有统计学意义（P〈0．05）；观察组产妇术后有出汗发热、呕吐腹泻等不良反应的发生率为5．3％（4／75），对照组不良反应的发生率为6．7％（5／75）。两组之间无显著差异（P〉0．05），未经特殊处理24h后均缓解。结论欣母沛防治高危剖宫产孕妇产后出血的临床有效率高，疗效较好，术后出血量少，不良反应少，安全性高，值得临床推广应用。
Objective To investigate the clinical efficacy of hemabate in preventing postpartum hemorrhage in high risk pregnancy women after cesarean section. Methods All 150 pregnant women which may cause uterine and risk fac- tors for cesarean section were selected in our hospital from October 2009 to June 2012. They were randomly divided into the observation group （75 cases） and the control group （75 cases）. The observation group was given hemabate 250 μg after the delivery of the fetus. While the control group was given oxytocin 20 U to the palace and intravenous infu- sion of oxytocin 20 U. The clinical efficacy of the two groups was observed and the amount of bleeding after 2 h and the amount of bleeding after 24 h as well as the adverse reactions were recorded. Results The total effective rate of the observation group was 93.3% （70/75）, significantly higher than 74.7% （56/75） of the control group, the difference was statistically significant （P〈0.05）, the blood loss after 2 h and 24 h of the observation group was （185.5±45.4） mL and （302.5±56.3） mL, significantly less than （287.5±55.7）mL and （403.8±64.2） mL of the control group, the difference was statistically significant （P〈0.05）, the rate of adverse reactions including sweating, fever, vomiting and diarrhea of the ob- servation group was 5.3% （4/75）, the rate of adverse reactions of the control group was 6.7% （5/75）, there was no signifi- cant difference between the two groups （P〉0.05）, and they were all relived in 24 h without any special treatment. Con- clusion The usage of hemabate in preventing postpartum hemorrhage in high risk pregnancy women after cesarean section had good clinical efficacy, less postoperative bleeding ang adverse reactions. It is safety and worth promotion and application in clinical.
出处
《中国现代医生》
2013年第30期115-117,共3页
China Modern Doctor
关键词
欣母沛
剖宫产
产后出血
Hemabate
Cesarean section
Postpartum hemorrhage
