摘要
目的分析南京医科大学第二附属医院2012年药品不良反应(adverse drug reaction,ADR)发生的特点和规律,为促进合理用药提供依据。方法对2012年148例有效不良反应报告,按照患者性别、年龄、给药途径、药品种类、涉及的器官或系统及其临床表现等方面进行统计分析。结果 148例不良反应报告中,10岁以下儿童及70岁以上老年人发生最多;静脉滴注给药引起的不良反应最多,占81.08%;抗菌药物引起的不良反应最多,占63.51%;ADR的临床表现以皮肤及其附件的损害多见,占60.14%。结论应加强不良反应监测,保证用药安全。
Objective To analyze the characteristics and regularity of adverse drug reaction （ADR） occurred in the second affiliated hospital of Nanjing Medical University in 2012, and of- fer some information about rational drug use.Methods 148 effective ADR case reports collected in our hospital were analyzed statistically according to patients＇ age and sex, route of adminis- tration, category of drug, organs and systems involved, and the clinical manifestation of the ADR.Results Most of the 148 ADR cases were of the children under tO and the old people over 60 years, 81.08% induced by intravenous dripping injection, and 63.51% were induced by anti- infective drugs. The clinical manifestations of ADR were mainly lesions of skin and its appenda- ges involving 60.14%.Conclusion It is important to strengthen ADR monitoring and ensure safe medication.
出处
《湖北民族学院学报（医学版）》
2013年第4期62-64,共3页
Journal of Hubei Minzu University(Medical Edition)
关键词
药品不良反应
监测
合理用药
adverse drug reaction
monitoring
rational drug use
