摘要
目的:分析南京医科大学第二附属医院2010年药品不良反应(ADR)发生的特点和规律,为合理用药提供依据。方法:对我院205例ADR报告,按照患者性别、年龄、给药途径、药品种类、涉及的器官或系统及其临床表现等方面进行统计分析。结果:静脉滴注给药引起的不良反应例数最多(171例,83.41%);抗菌药引起的不良反应比例最高(116例,55.24%);60岁以上患者ADR的构成比高于其他年龄段;ADR的临床表现以皮肤及其附件的损害多见,其次为消化系统损害。结论:应加强ADR的监测,确保用药安全。
Objective :To analyze the characteristics and regularity of adverse drug reaction (ADR) occurring in the Second Affiliated Hospital of Nanjing Medical University in 2010 to offer some information about rational drug use. Method :205 cases of ADR reports collected in our hospital were statistically analyzed in respect of patients' age and sex, route of administration, category of drug, organs and systems involved, and the clinical manifestation of ADRs, Result:The proportion of ADRs caused by intravenous drip was the most( 171 cases, 83.41% ), anti-infective caused the highest proportion of ADRs ( 116 cases, 55.24% ), the proportion of ADRs caused by patients above 60 was higher than that in other age group, and the main presentation of ADR was damage of skin and its appendages, and the next was the circulatory system. Conclusion:It is important to strengthen ADR monitoring and ensure safe medication.
出处
《药物流行病学杂志》
CAS
2011年第10期516-519,共4页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
不良反应监测
抗菌药
中药注射剂
Adverse drug reaction
Adverse drug reaction monitoring
Anti-infective drug
Traditional Chinese medicine injection