摘要
目的:利用星点设计-效应面法优选紫荆皮挥发油的提取工艺。方法:以挥发油提取量为因变量,在单因素试验基础上,选取浸泡时间、提取时间、加水量为自变量,通过对不同因素各水平的多元线性回归及二项式拟合,采用星点设计-响应面法优选紫荆皮挥发油的提取工艺,并进行预测分析。结果:挥发油的最佳提取工艺条件为浸泡时间1 h,提取时间5 h,加水量14倍;挥发油提取率0.8%,挥发油平均质量0.391 2 g,与预测值(0.391 5 g)的偏差较小。结论:优选的提取工艺简便合理、稳定、可预测性良好。
Objective： To optimize extraction technology of volatile oil from Cortex Cercis Chinensis by central composite design and response surface methodology. Method： With yield of volatile oil as dependent variable,based on single factor tests,central composite design-response surface methodology was adopted to optimize extraction technology by taking soaking time,extraction time and the amount of water as independent variables,through multiple linear regression and binomial fitting of each level of independent variables to prediction analysis of extraction technology. Result： Optimum process conditions were as follows：soaked 1 h with 14 times the amount of water,extraction time 5 h;Yield of volatile oil was 0.8%,average mass of volatile oil was 0.391 2 g with a small deviation between the predicted value（0.391 5 g）. Conclusion： This optimized extraction process was simple and reasonable with a good predictability.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第23期14-17,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
甘肃省科技厅科技支撑计划项目(1104FKCA121)
关键词
紫荆皮
星点设计-效应面法
水蒸气蒸馏法
单因素试验
挥发油
Cortex Cercis Chinensis
central composite design-response surface methodology
steam distillation method
single factor test
volatile oil
