摘要
目的:为制备浓缩型白术颗粒饮片,以水作溶剂,用超声波强化白术有效成分的提取。方法:研究了超声波条件下影响浸提的几个因素,包括料液比、超声功率、超声时间、浸泡时间、粒度等,并通过响应面法优化工艺条件。结果:当白术颗粒度为0.1 mm,提取次数为3次,超声前浸泡时间为30 min,液固比为10∶1,超声后浸泡时间为2.6 h,超声时间为15.5 min,超声功率为531 W时,白术有效成分提取效果最佳。白术有效成分保留88.5%,浓缩1.6倍。结论:超声波方法可较好地应用于白术有效成分的提取浓缩,通过响应面法得到一个能较好预测试验结果的模型方程。
Objective： To create Atracrylode macrocephala inspissation decoction pieces. The effect of ultrasonic wave on extraction of the active components in A. macrocephala was studied in a water solution. Methed： The factors including the ratio of material to liquid, ultrasonic power, ultrasonic time, soaking time, particle size etc, were studied. The best extraction method was found through the response surface method. Rest： The best extraction method was found as follows： the granularity of matexial 0.1mm, the repetition times of ultrasonic process 3 times, the soaking time before the ultrasonic process 30 min, the ratio of liquid to material 10：1, the soaking time after the ultrasonic process 2.6 h, the time of the ultrasonic wave 15.5 min, the power of the ultrasonic wave 531 W, the rate of reservation of active components 88.5%, the rate of inspissation 1.6. Conclusion： The ultrasonic wave can used in the extraction of the active components in A. macrocephala and a model equation that can be used to prodict the experiment was get through the response surface method.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2006年第7期549-552,共4页
China Journal of Chinese Materia Medica
关键词
白术
药效成分
提取
超声波
响应面法
Atractylode macrocephala
active component
extraction
ultrasonic wave
response surface method
