摘要
Benzoic and salicylic acids in ointment sample were extracted with a 75% tehanol solution.The extracts are neutralized with tetramethylammonium hydroxide solution.Tetramethyl ammonium salts of benzoic and salicylic acids formed further react with 1 iodobutane directly in N,N dimethylformamide solution to form butyl esters of the corresponding acids.The separation of the butyl esters was carried out on column packed with 5% SE 30/102 Silanized white support.This method is simple and accurate.
Benzoic and salicylic acids in ointment sample were extracted with a 75% tehanol solution.The extracts are neutralized with tetramethylammonium hydroxide solution.Tetramethyl ammonium salts of benzoic and salicylic acids formed further react with 1 iodobutane directly in N,N dimethylformamide solution to form butyl esters of the corresponding acids.The separation of the butyl esters was carried out on column packed with 5% SE 30/102 Silanized white support.This method is simple and accurate.
出处
《化学研究与应用》
CAS
CSCD
2000年第5期557-559,共3页
Chemical Research and Application
关键词
苯甲酸
水杨酸
气相色谱
苯甲酸软膏
消毒药
gas chromatography
esterification
salicylic acid
benzoic acid
ointment
