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儿童少年期与青年期首发精神分裂症患者临床特征对照研究 被引量:6

Clinical features of childhood/juvenile and adolescence firstonset schizophrenia
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摘要 目的探讨住院儿童少年期与青年期首发精神分裂症患者临床特征。方法将60例〈15岁的儿童少年期首发精神分裂症患者设为儿童少年组,85例≥15岁的青年期首发精神分裂症患者设为青年组,对两组患者的病历资料进行对照分析。结果儿童少年组与青年组家族史阳性率分别为21.7%、21.2%,两组比较差异无显著性(P〉0.05)。儿童少年组视幻觉、感知综合障碍、焦虑抑郁、孤僻退缩症状检出率显著高于青年组(P〈0.05或0.01),妄想症状检出率显著低于青年组(P〈0.01)。结论儿童少年和青年期精神分裂症发病与家族遗传密切相关,临床症状与发病年龄和心理行为发育状况有明显的相关性;儿童少年期患者感知觉障碍、焦虑抑郁、孤僻退缩和冲动行为症状较青年期患者多见,思维内容障碍相对较少,情感平淡阳性率与成人期大体相当。 Objective To explore the clinical features of hospitalized childhood/juvenile and adolescence first-onset schizophrenia. Methods Sixty first-onset schizophrenics 〈 15 years were assigned to child- hood/juvenile group and 85 ones 15 to adolescence group, their data of medical history were contrastive ly analyzed. Results Positive rate of family history was respectively 21. 7% in childhood/juvenile and 21.2% in adolescence group, which showed no significant difference (P〈0.05). The detection rate of vis ual hallucination, psychosensory disturbance, anxiety/depression, autism/retraction were significantly higher (P〈0.05 or 0.01) and that of delusion lower (P〈0.01) in childhood/juvenile than adolescence group. Conclusion Onset of childhood/juvenile and adolescence schizophrenia is closely related to family heredity, clinical symptoms are related to age of onset and psychological and behavioral development notably psychosensory disturhance, anxiety/depression, autism/retraction and impulsive behavior are more and thought disturbance less in childhood/juvenile than adolescence group, positive rate of apathy is in general equivalent to adults.
出处 《临床心身疾病杂志》 CAS 2013年第3期232-234,共3页 Journal of Clinical Psychosomatic Diseases
关键词 精神分裂症 儿童少年期 青年期 临床特征 阳性与阴性症状量表 Schizophrenia childhood/juvenile adolescence clinical feature PANSS
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