期刊文献+

多巴胺D_2受体的拮抗解离假说 被引量:2

下载PDF
导出
摘要 多巴胺D2受体的拮抗解离假说是继5HT/DA平衡拮抗学说之后产生的又一试图解释第2代抗精神病药物作用机理的学说,本文就其产生的背景和意义作一介绍。
作者 童建明
出处 《国际精神病学杂志》 2006年第4期196-199,共4页 Journal Of International Psychiatry
  • 相关文献

参考文献13

  • 1Meltzer HY. Clinical studies on the mechanism of action of clozapine: the dopamine-serotoninhypothesis of schizophrenia.Psychopharmacology, 1989; 99: S18-S27. 被引量:1
  • 2Meltzer HY, Matsubara S, Lee J. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 Pki values. J Pharmacol Exp Ther. 1989; 251 :238-246. 被引量:1
  • 3Kapur S, Remington G. Dopamine D2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient. Biol Psychiatry, 2001; 50: 873- 883. 被引量:1
  • 4久住一郎,小山司.ドバミンD2受容体のfast dissociation反說をゃぐつて.臨床精神医学,2005,34(4):453-458 被引量:1
  • 5Seeman P. Atypical antipsychotics: mechanism of action. Can J Psychiatry, 2002; 47 : 27 - 38. 被引量:1
  • 6Garris PA, Wightman RM. Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex and striatum,an in vivo voltammetry study. J Neurosci. 1994; 14: 442-450. 被引量:1
  • 7Koepp M J, Gunn RN, Lawrence AD, et al. Evidence for striatal dopamine release during a video game. Nature, 1998;393 : 266-268. 被引量:1
  • 8Kapur S, Zipursky R, Jones C, et al. A positron emission tomngraphy study of quetiapine in schizophrenia A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch Gen Psychiatry, 2000;57:553 - 559. 被引量:1
  • 9Seeman P, Tallerico T. Rapid release of antipsychotic drugs from dopamine D2 receptors; An explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine. Am J Psychiatry, 1999; 156: 876- 884. 被引量:1
  • 10黑木俊秀.セロトニン·ドバミン反說の现在.臨床精神医学,2005;34(4):441~451 被引量:1

同被引文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部