摘要
目的评价厄他培南治疗老年社区获得性肺炎的疗效和安全性。方法 100例老年(≥65岁)社区获得性肺炎患者随机分为2组,每组50例。实验组给予注射用厄他培南1.0 g,1次/d,对照组给予莫西沙星注射液400 mg,1次/d,两组疗程均为7～14 d。观察治疗前后两组的临床疗效。结果实验组治疗有效率为92%,细菌清除率为88.9%;对照组治疗有效率为76%,细菌清除率为69.8%;两组间比较差异有统计学意义(P<0.05)。结论厄他培南治疗老年社区获得性肺炎临床疗效良好,不良反应较少,安全性高。
Objective To evaluate the efficacy and safety of ertapenem on the community-acquired pneumonia in elderly patients. Methods 100 cases of community-acquired pneumonia in elderly patients（aged≥65 years） were randomly divided into two groups,the experiment group was given ertapenem 1g,once a day for 7～14 days and the control group was given moxifloxacin injection 400 mg,once a day for 7～14 days.The clinical effect was observed before and after the treatment. Results The effective rate and bacteriological clearance rate of the experiment group were 92% and 88.9% and it were 76% and 69.8% of the control group.There was significant difference between the two groups（P0.05）. Conclusion The clinical improvement appears much better by ertapenem treatment,and it is safe and effective to therapy community-acquired pneumonia in elderly patients.
出处
《实用药物与临床》
CAS
2013年第3期229-231,共3页
Practical Pharmacy and Clinical Remedies
关键词
厄他培南
社区获得性肺炎
老年
Ertapenem
Community-acquired pneumonia
Elderly patients
