摘要
ε-聚赖氨酸(ε-PL)是一种重要的氨基酸同聚物,可通过微生物发酵的方法进行生产。ε-PL在酸碱和高温环境中非常稳定,抑菌谱广,可溶于水、可降解、可食用、无毒。鉴于其显著特点,ε-PL及其衍生物具有广阔的应用前景,如食品防腐剂、食疗剂、生物可降解纤维、乳化剂、高吸水性凝胶、抗癌增效剂、药物载体及生物芯片包衣等。目前,已有日本、韩国、美国等国家批准其作为食品防腐剂进行应用。微生物在生长、繁殖和代谢过程中需要碳源和氮源作为营养物质,还需要一些微量元素作为其生理活性物质的组成或生理活性作用的调节物质。培养基中添加有多种组分,本文对ε-聚赖氨酸的理化和生物学活性以及培养基成分(如碳源、氮源、无机盐等)对ε-聚赖氨酸生物合成的影响进行了综述。
ε- poly - L - lysine （ ε- PL） is a basic homo - poly - amino acid, which can be produced by microbe.ε- PL is stable at both acidic and alkaline and high temperature conditions, and it has a wide antimicrobial spectrum. Besides, ε- PL is water soluble, biodegradable, edible, cationic and nontoxic. Due to these properties, ε- PL and its derivatives have a broad range of applications such as food preservatives, dietary agent, biodegradable fibers, emul- sifying agent, highly water absorbable hydrogels, anticancer agent enhancer, drug carriers, biochip coatings. It used as a food preservative in Japan, South Korea, the USA, and other countries. In a certain range of concentration, car- bon and nitrogen sources and some trace elements play a very important role in the growth and metabolism of microorgan- ism as nutrient substances, a component of physiological active substance or a regulator of biological reaction. The physical, chemical and biological properties of e - poly - L - lysine and effects of medium components, such as carbon and nitrogen sources, mineral salts, on its biosynthesis were reviewed in this paper.
出处
《中国食品添加剂》
CAS
北大核心
2013年第1期208-213,共6页
China Food Additives
基金
国家科技支撑计划项目(2012BAD37B05)
农业科技成果转化资金项目(2012GB2B100101)
关键词
金属离子
Ε-聚赖氨酸
性质
生物合成
metal ion
ε- poly - L - lysine
characteristic
biosynthesis
