期刊文献+

噬血细胞综合征的^(18)F-FDG PET/CT影像学特点 被引量:7

18F-FDG PET/CT imaging characteristics of the hemophagocytic syndrome
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摘要 目的探讨噬血细胞综合征的18F-FDG PET/CT显像的影像学特点。方法回顾性分析我院7例HLH临床资料和18F-FDG PET/CT影像资料。结果 7例患者均因不明原因发热入院,7例患者均符合HLH诊断指南2004修订版的标准。肝脏增大4例,3例合并FDG摄取增高,脾脏增大6例,5例合并FDG摄取增高,2例出现全身多发淋巴结增大并FDG摄取增高,2例表现为脑皮质FDG摄取弥漫性减低,6例出现肺部改变(肺炎、肺不张、胸腔积液等)。结论认识该疾病的18F-FDG PET/CT影像表现,有助于提高该疾病的诊断率。 Objective To summarize the imaging characteristics of 18F-FDG PET/CT in patients with hemophagocytic lymphohistiocytosis(HLH).Methods The clinical data and image data by whole body 18F-FDG PET/CT of 7 patients with HLH were retrospectively reviewed.Results 7 patients with unknow fever were admitted to our hospital and underwent a 18F-FDG PET/CT examination.All patients were met the revised diagnostic guidelines for HLH.There were 6 cases of splenomegaly with diffuse intense FDG uptake,4 cases of hepatomegaly with diffuse intense FDG uptake,3 cases of intense FDG uptake in the bone marrow,2 cases of intense FDG uptake in the enlarged lymph node,2 cases of diffuse declined FDG uptake in ectocinerea,and 6 cases having pulmonary abnormality including pneumonia,atelectasis,and pleural effusions.Conclusion Clinicians and radiologists should be aware of the 18F-FDG PET/CT imaging manifestations of HLH in order to improve the diagnostic accuracy.
出处 《医学影像学杂志》 2012年第7期1201-1204,共4页 Journal of Medical Imaging
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参考文献10

  • 1Johnson TS,Villanueva J,Filipovich AH. Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders[J].Journal of Immunological Methods,2011.1-13. 被引量:1
  • 2Tang YM,Xu XJ. Advances in hemophagocytic lymphohistiocytosis:pathogenesis,early diagnosis/differential diagnosis,and treatment[J].Scientific World Journal,2011.697-708. 被引量:1
  • 3Henter JI,Horne A,Arico M. HLH-2004:Diagnostic and therapeutic guidelines for hemophagocytic lymphohistio-cytosis[J].Pediatric Blood & Cancer,2007.124-131. 被引量:1
  • 4Risma K,Jordan MB. Hemophagocytic lymphohistiocytosis:updates and evolving concepts[J].Current Opinion in Pediatrics,2012.9-15. 被引量:1
  • 5Suga K,Kawakami Y,Hiyama A. F-18 FDG PET/CT findings in a case of T-cell lymphoma-associated hemophagocytic syndrome with liver involvement[J].Clinical Nuclear Medicine,2010.116-120. 被引量:1
  • 6Corapcioglu F,Oncel S,Berberolu K. False positivity of FDG-PET during hemophagocytic lymphohistiocytosis in a child with Hodgkin lymphoma in remission[J].Journal of Pediatric Hematology Oncology,2009.74-75. 被引量:1
  • 7Fitzgerald NE,MacClain KL. Imaging characteristics of hemophagocytic lymphohistiocytosis[J].Pediatric Radiology,2003.392-401. 被引量:1
  • 8Chung TW. CNS involvement in hemophagocytic lymphohistiocytosis:CT and MR findings[J].Korean Journal of Radiology,2007.78-81. 被引量:1
  • 9杨双,张莉,马宏浩,贾晨光,吴润辉,申昆玲.噬血细胞性淋巴组织细胞增生症前瞻性研究[J].实用儿科临床杂志,2009,24(3):181-184. 被引量:5
  • 10杨双,郑胡镛,谢静,吴润晖,马晓丽,周翾.噬血细胞性淋巴组织细胞增生症47例[J].实用儿科临床杂志,2007,22(15):1149-1151. 被引量:2

二级参考文献31

  • 1Henter JI, Home A, Arico M, et al. HLH - 2004 : Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis [ J ]. Pediatr Blood Cancer,2007,48 (2) : 124 - 131. 被引量:1
  • 2Rouphael NG, Talati NJ, Vaughan C, et al. Infections associated with haemophagocytic syndrome [ J ]. Lancet Infect Dis, 2007,7 ( 12 ) : 814 - 822. 被引量:1
  • 3Zur Stadt U, Beutel K, Kolberq S,et al. Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: Molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A [ J]. Hum Mutat,2006,27( 1 ) :62 -68. 被引量:1
  • 4Ma KA, Frayer RW, Filipovieh AH,et al. Aberrant maturation of mutant perforin underlies the clinical diversity of hemophagocytic lymphohistiocytosis [ J ]. J Clin Invest,2006,116 ( 1 ) : 182 - 192. 被引量:1
  • 5Zur Stadt U, Schmidt S, Kasper B, et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL)type -4 to chromosome 6q24 and identification of mutations in syntaxin 11 [ J ]. Hum Mol Genet, 2005,14 (6) :827 -834. 被引量:1
  • 6Trapani JA, Voskoboinik I. Infective, neoplastic, and homeostatic sequelae of the loss of perforin function in humans[ J]. Adv Exp Med Biol, 2007,601:235 -242. 被引量:1
  • 7Imashuku S. Advances in the management of hemophagocytic lymphohistiocytosis[ J]. lnt J Hematol,2000,72( 1 ) : 1 - 11. 被引量:1
  • 8Marc T, Marina C, Stephane B, et al. Hematopoietic stem cell transplantation in hemophagocytic lymphohistiocytosis: A single center report of 48 patients [ J ]. Pediatrics,2006,117 ( 4 ) : 743 - 750. 被引量:1
  • 9Gershburg E, Pagano JS. Epstein-Barr virus infections:Prospects for treatment [ J ]. J Antimicrobl Chemother, 2005,56 ( 2 ) : 277 - 281. 被引量:1
  • 10Kawashiri S, Nakamura H, Kawakami A,et al. Emergence of Epstein- Barr virus - associated haemophagocytic syndrome upon treatment of systemic lupus erythematosus [ J ]. Lupus,2006,15 ( 1 ) :51 - 53. 被引量:1

共引文献5

同被引文献91

  • 1马小军,王爱霞,邓国华,盛瑞媛.不明原因发热449例临床分析[J].中华内科杂志,2004,43(9):682-685. 被引量:116
  • 2林冰.发热待查住院452例临床资料对比分析[J].疑难病杂志,2006,5(6):424-426. 被引量:15
  • 3Gholam C, Grigoriadou S, Gilmour KC, et al. Familial haemophago- eytie lymphohistioeytosis: Advances in the genetic basis, diagnosis and management, Clin Exp Immunol, 2011,163(3) :271-283. 被引量:1
  • 4Janka GE. Familial and acquired hemophagoeytic lymphohistiocy- tosis. Eur J pediatr, 2007,166(2) :95-109. 被引量:1
  • 5Henter J, Samuelsson-Horne A, Arico M, et al. Treatment of he- mophagoeytic lymphohistioeytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood, 2002,100(7):2367-2373. 被引量:1
  • 6Celkan T, Berrak S, Kazanei E, et al. Malignancy-associated he-mophagocytic lymphohistiocytosis in pediatric cases: A multi- center study from Turkey. Turk J Pediatr, 2009,51 (3) : 207-213. 被引量:1
  • 7Gupta AA, Tyrrell P, Valani R, et al. Experience with hemoph- agocytic lymphohistiocytosis/macrophage activation syndrome at a single institution. Pediatr Hematol Oncol, 2009,31(2):81-84. 被引量:1
  • 8Han AR, Lee HR, Park BB, et al. Lymphoma-assoeiated he- mophagocytic syndrome: Clinical features and treatment out- come. Ann Hematol, 2007,86(7) :493-498. 被引量:1
  • 9Tong H, Ren Y, Liu H, et al. Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: Compari- son of T-cell lymphoma with and without hemophagocytic syn- drome. Leuk Lymphoma, 2008,49(1) :81-87. 被引量:1
  • 10Corapcioqlu F, Oneel S, Berberoqu K, et al. False positivity of FDG-PET during hemophagoeytie lymphohistioeytosis in child with Hodgkin lymphoma in remission. J Pediatr Hematol Oneol, 2009,31 ( 1 ) : 74-75. 被引量:1

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