摘要
目的探讨精神分裂症患者内部动机、眼区基本情绪识别能力与其阴性症状三者间的关系。方法采用精神分裂症内部动机量表(IMI-SR)和眼区基本情绪识别任务(EBEDT)对61例精神分裂症患者(患者组)和50名健康志愿者(对照组)作评估,同时患者接受阳性与阴性症状量表(PANSS)评估。结果患者组IMI-SR总分、兴趣性因子分和选择性因子分均低于对照组(P<0.01)。患者组EBEDT总正确率显著低于对照组(P<0.01),6种基本情绪正确率组间比较,差异均有统计学意义(P<0.01);相关分析显示,患者IMI-SR总分、EBEDT总正确率与PANSS阴性症状分均两两相关(P<0.01);回归分析显示,内部动机可直接预测阴性症状水平(β=-0.296,P<0.05),在情绪识别能力与阴性症状间起着完全中介作用。结论精神分裂症患者存在内部动机和情绪识别损害,情绪识别能力通过内部动机的完全中介效应对阴性症状程度产生影响。患者内部动机损害、眼区情绪认知缺陷和阴性症状三者间可能具有某种共同的病理生理基础。
Objective To explore the relationship among intrinsic motivation,eye-expression recognition and negative symptoms in patients with schizophrenia.Methods 61 schizophrenic patients without treatment(patients group) and 50 healthy volunteers(control group) were assessed by means of the Intrinsic Motivation Inventory for Schizophrenia Research(IMI-SR) and the Eye Basic Emotion Discrimination Task(EBEDT).The patients were also assessed by the Positive and Negative Syndrome Scale(PANSS).Results Compared with the healthy controls,patients had significantly decreased IMI-SR total score and subscores of interest and choice(P0.01).Schizophrenic patients had significantly less total correct rate(P0.01) of EBEDT compared with normal controls,and 6 kinds of basic emtion correct rate of EBEDT also had difference between the two groups(P0.01).Correlation analysis showed that IMI-SR total score,EBEDT total correct rate and PANSS negative symptoms score were correlated each other.Regression analysis showed that intrinsic motivation directly predicted negative symptoms level(β=-0.296,P0.05)and completely mediated the relationship between eye-emotion regcognition ability and negative symptoms level.Conclusion Schizophrenic patients have impairments of intrinsic motivation and eye-emotion recognition ability,and the intrinsic motivation is a complete mediator by which eye-emtion regcognition ability influences negative symptoms,suggesting that intrinsic motivation deficits may share a common pathophysiological base with the impairment of emotion recognition and negative symptoms.
出处
《安徽医科大学学报》
CAS
北大核心
2013年第1期77-81,共5页
Acta Universitatis Medicinalis Anhui
基金
国家自然科学基金(编号:81171273)
安徽省高校省级自然科学研究重点项目(编号:KJ2010A165)
关键词
精神分裂症
内部动机
阴性症状
眼部
情绪
认知
schizophrenia
intrinsic motivation
negative symptoms
eye
emotion
recognition