摘要
目的:了解我院药品不良反应(ADR)的发生特点及一般规律,为临床安全用药提供依据。方法:对我院2009～2011年上报药品不良反应监测中心的164例ADR报表进行分类、统计。结果:164例ADR病例中,中老年的患者较多(77.45%);构成比最高的给药途径为静脉滴注(90.24%);164例ADR共涉及46种药品,其中构成比最高的为抗感染药(占29.88%);临床表现以皮肤及附件最常见(占40.49%)。结论:ADR的发生与患者体质、给药途径有关;在给药过程中应密切观察,一旦发生ADR应及时处理;并加强ADR的上报及宣传,为临床用药安全、有效、合理提供保障。
Objective： This manuscript is to investigate the characteristics and general rules of the adverse drug reactions induced by traditional medicines in our hospital, so as to provide reference for rational clinical use of drugs. Methods： 164 ADR cases were collected from our hospital from 2009 to 2011, and were analyzed statistically by State ADRM monitoring Center. Results： The ADRs were mostly occurred in middle-aged patients （77.45%） in the total 164 ADR cases. Intravenous drip infusion was the major route of administration （90.24 %）. A total of 46 kinds of traditional medicines were involved in the 164 ADR cases. The incidence of the highest were antibiotics （29.88 %）. Skin and appendages were the most common clinical manifestations of ADR （40.49%）. Conclusion： The occurrence of ADR is associated with patients＇ physique and route of administration. Close observation should be carried out during medication. Safe and reasonable use of drugs can be guaranteed when ADR cases are disposed timely.
出处
《药品评价》
CAS
2012年第29期30-32,42,共4页
Drug Evaluation
