摘要
目的探讨中药"通腑洁肠汤"对不全性肠梗阻的老年结直肠癌患者术前肠道准备的安全性、有效性及其临床意义。方法术前随机给予77例60岁以上伴不全性肠梗阻的结直肠癌患者口服中药"通腑洁肠汤"或聚乙二醇电解质散行肠道准备,前者为中药组,39例,后者为对照组,38例,对比两组患者肠道清洁度,肠道准备过程中及术后并发症。结果中药组肠道清洁程度达到优者(Ⅰ级)34例,良(Ⅱ级)4例,一般(Ⅲ级)1例,差(Ⅳ级)0例,优良率达97.44%,对照组各级病例数分别为32例、2例、1例和3例,优良率为89.47%,两组优良率差异无统计学意义,P>0.05。两组肠道准备过程中并发完全性肠梗阻、肠穿孔、水电解质紊乱,术后并发吻合口漏、切口感染的病例数分别为0例、0例、0例,0例、1例(2.56%)和3例(7.89%)、1例(2.63%)、0例,1例(2.63%)、2例(5.26%)。结论中药"通腑洁肠汤"对老年不全性肠梗阻的结直肠癌患者具有良好的肠道清洁作用,且安全性高,并发症少,值得临床推广采用。
Objective To explore the safety, effect and clinical significance of ＂Tongfu Jiechang Soup＂ on intestinal preperation preoperation of elderly eolorectal cancer patients combined with incomplete ileus. Methods Randomized study was carried out in 77 colorectal cancer patients combined with incomplete ileus who were 60 years old or above. 39 and 38 patients were arranged to take ＂Tongfu Jiechang Soup＂ or poly- ethylene glycol electrolyte balanced solution to clean intestinal tract preoperation respectively as treatment group or control group. Then the intestinal cleaness and the complications during the intestinal preparation and postoperation in the two groups were observed and compared. Results Intestinal cleaness of 34 patients in treatment group was perfect （grade Ⅰ） and 4 was good （Ⅱ）, 1 was common （Ⅲ）, 0 was bad （Ⅳ）. Meanwhile, the corresponding results were 32, 2, 1 and 3 in control group. The rate of grade Ⅰ and Ⅱ in treatment group was 97.44%, higher than control group, 89.47%, but no remarkable difference wasfound （ P 〉0.05）. There was 0, 0, 0, 0 and 1（2.56%） patient in treatment group ran into complete ileus, enterobrosis, disturbance of water or electrolyte, anastomotic leakage and incision infection respectively. The corresponding results in control group were 3（7.89%）, 1（2.63%）, 0, 1（2.63%） and 2（5.26%）. Conclusion ＂Tongfu Jiechang Soup＂ on intestinal preperation of elderly colorectal cancer patients combined with incomplete ileus is characterized by well cleaness, high safety, few complications and low cost, thus it is worth of clinical application.
出处
《结直肠肛门外科》
2012年第4期213-216,共4页
Journal of Colorectal & Anal Surgery
基金
四川省卫生厅资助项目(编号050065)
关键词
中药
老年
结直肠癌
肠梗阻
肠道准备
Traditonal Chinese medicine
Elderly patients
Colorectal cancer
Lleus
Lntestinal prepa-ration
