摘要
目的探讨年龄和性别对健康成人血浆D-二聚体浓度的影响。方法以西门子医疗诊断公司的INNOVANCE0D-Dimer和日本Sysmex公司的CAl500全自动凝血分析仪检测了583例健康体检者血浆D-二聚体，所得数据以SPSSl0．0统计软件包中有关处理方法加以处理分析。结果血浆D-二聚体总体水平随着年龄增长而增高（r=0．27，F=3．28，P〈O．05）；年长女性（〉40岁）血浆D-二聚体总体水平明显高于同龄男性（t=2．24，P〈0．01）；年轻组（〈40岁）的结果提示无性另4差异（t=0．983，P〉0．05）；10岁年龄分层分析显示，男性50岁以下血浆D-二聚体基本保持稳定，而女性〉40岁便随年龄增加而升高，且明显高于同龄男性（t=2．24，P〈0．01）。结论健康人血浆D-二聚体随年龄增加而升高；年长女性高于男性。
Objective To explore Effect of age and gender on plasma D-dimer concentration in healthy adult. Methods Plas- ma D-dimer concentration of 583 healthy subjects were determined with INNOVANCE D-Dimer（Siemens Healthcare Diag- nostics Products GmbH） and Sysm CA-1500 system. The related statistical analysis was completed by SPSS software package Results D-dimer concentrations were significantly higher in aged group than that in young group （ r= 0.27, F=3.28, P〈0. 05）. Plasma D-dimer concentrations in elder women （〉40 year old） were significantly higher than that in the same age men （t=2.24, P〈0. 01）. In contrast,plasma D-dimer concentration in young group （〈40 year old） had no gender difference （t=0. 983, P〉0. 05）. The analysis stratified by 10 year old revealed that D-dimer concentrations were stable in less than 50 year old men,but the D-dimer concentration in women increased with age in no less than 40 year old group. Con- clusion In healthy people, plasma D-dimer concentration increased with age, and plasma D-dimer concentration in elder women（〉40 year old） were significantly higher than that in the same age men.
出处
《现代检验医学杂志》
CAS
2012年第4期96-97,共2页
Journal of Modern Laboratory Medicine
