摘要
目的探讨高水平D-二聚体(DD)在血栓性疾病诊断中的临床价值。方法选择60例DD≥2 000ng/mL的患者为研究对象,并行下肢血管超声及肺动脉造影检查。结果当DD≥2 000ng/mL时,妇科疾病发生下肢深静脉血栓或肺栓塞的比例为23.3%。恶性肿瘤晚期、术后卧床>2d及中期妊娠下肢深静脉血栓发生率高。结论 DD明显升高有助于血栓性疾病的早期诊断,但由于干扰因素影响,临床上需重点监管血栓形成的高风险人群。
Objective To investigate the clinical value of high level plasma D-dimer (DD) for diagnosing thrombotic disease. Methods A total of 60 women with DD level more than 2 000 ng/mL were selected in this study,then underwent venous ultrasonography of the lower extremities and computed tomography pulmonary angiography. Results Gynecological diseases with plasma DD level 2 000 ng/mL and more occurred deep venous thrombosis (DVT) of lower extremities or pulmonary thromboembolism (PTE) at a rate of 23.3%.Late stage of gynecological carcinomas,staying in bed more than 2 days after operation,and midtrimester of pregnancy had a high risk of developing DVT. Conclusion High level plasma DD provides a good value to diagnose early thromboembolic events,but considering interference factors,it is need to supervise people with high risk of thrombotic disease.
作者
梁凌云
陈艳霞
何艳
LIANG Lingyun;CHEN Yanxia;HE Yan(Department of Gynecology,the First Teaching Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830054,China)
出处
《检验医学与临床》
CAS
2019年第10期1328-1331,共4页
Laboratory Medicine and Clinic
基金
新疆维吾尔自治区自然科学基金项目(2016D01C283)
关键词
D-二聚体
静脉血栓
肺栓塞
D-dimer
venous thrombosis
pulmonary thromboembolism
