摘要
目的探讨倍他乐克佐治心衰的疗效及对血清中脑利钠肽(BNP)和白细胞介素-12(IL-12)的影响及其临床意义。方法收集我院诊治的102例心力衰竭患者,依入院顺序分为观察组和对照组各51例,对照组应用常规治疗,观察组在常规治疗基础上加用倍他乐克,观察两组的疗效及对患者血清中BNP和IL-12的影响。结果观察组治疗后的总有效率明显优于对照组(P<0.05)。两组治疗后血清中BNP和IL-12的表达明显低于治疗前,但观察组治疗前、后BNP和IL-12的减少值明显高于对照组(P<0.05)。结论心力衰竭患者应用倍他乐克进行辅助治疗,临床效果好,且能对血清中的BNP和IL-12的表达进行有效的调节,进而有效改善机体的体内环境,临床中可以积极应用。
Objective To observe the curative effect, BNP and IL-12 detection in patients with heart failure by Metoprolol succinate sustained-release tablets, for accumulating clinical experience, directing clinical work. Methods A total of 102 patients with chorinic heart failure were divided into two groups. The routine treatment were applied in the control group （51 cases）, the routine treatment and Metoprolol succinate sustained-release tablets were applied in the observation group （51 cases）. The curative effect and the detection of BNP and IL-12 detection were observed in two groups. Results The to tal effective rate was obviously higher in the observation group than the control group. The change values of BNP and IL l2 detection were obviously higher in the observation group than the control group after treatment. Conclusion The Meto prolol succinate sustained-release tablets can improve the curative effect, regulate the expressions of BNP and IL-12 in patients with heart failure, is worthy of being recommended in clinical treatment.
出处
《中国现代医生》
2012年第24期70-71,74,共3页
China Modern Doctor
