摘要
蒿属植物在世界各国胃肠道疾病传统防治中有广泛应用,现代药理研究验证了蒿属植物提取物及其活性成分异泽兰黄素、dehydryleucodine等的临床前及临床治疗效果。艾蒿、茵陈等蒿属植物是传统中药,具有广泛的药理活性;然而,国内对其在胃肠道疾病防治中的应用及现代研究相对滞后。主要综述了蒿属植物在胃肠道疾病防治中的药理作用及其机制研究进展,以期为蒿属植物的创新应用及中药现代化研究提供借鉴。
Artemisia L.species were used in gastrointestinal protection widely around the world.Modern researches showed that Artemisia L.plant extracts and their active constituents,eupatilin and dehydryleucodine,showed positive effects against gastrointestinal diseases in preclinical and clinical trials.Plants in Artemisia L.,such as A.verlotorum and A.scoparia,are widely used in traditional Chinese medicines（TCM） with a wide range of pharmacological activities.However,their application in prevention and treatment of gastrointestinal diseases and their modern researches have lagged behind in our country.This article reviews the pharmacologic effect and the mechanism of the plants in Artemisia L.for gastrointestinal protection,which could provide the reference for innovative application and modernization of TCM.
出处
《现代药物与临床》
CAS
2012年第3期304-308,共5页
Drugs & Clinic
关键词
蒿属植物
胃肠道疾病
药理作用
机制
plants in Artemisia L.
gastrointestinal diseases
pharmacologic effect
mechanism
