摘要
[目的]建立扶肾颗粒的质量标准。[方法]采用薄层色谱(TLC)法鉴别制剂中黄芪、当归、丹参、大黄、陈皮药材,用高效液相色谱(HPLC)法测定制剂中淫羊藿苷的含量。[结果]TLC斑点清楚,专属性强。淫羊藿苷0.048 5～0.97μg范围内与峰面积积分值呈良好线性关系(r分别为0.999 9);平均回收率分别为97.0%,相对标准偏差(RSD)分别为0.7%。[结论]所建标准可用于扶肾颗粒的质量控制。
[Objective] To establish the quality standard of Fushen granule. [Methods] Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix et Rhizoma Rhei and Pericarpium Citri Reticulatae in some preparations were identified qualitatively by ＇rLC and the content of icariine in Herba Epimedii was determined by HPLC. [Results] The TLC spots were distinctive and specific. The linear range of quercetin,kaempferide, isorhamnetin was 0.048 5-0.97 μg （r=0.999 9）.The average recovery rate was 97.0% （RSD=0.7%）. [Conclusion] The method is reliable, accurate, and reproducible for the quality control of Fushen granule.
出处
《天津中医药大学学报》
CAS
2011年第4期234-237,共4页
Journal of Tianjin University of Traditional Chinese Medicine
关键词
扶肾颗粒
薄层色谱法
高效液相色谱法
黄芪
当归
丹参
大黄
陈皮
淫羊藿
Fushen granule
TLC
HPLC
icariine
Radix Astragali
Radix Angelicae Sinensis
Radix SalviaeMihiorrhizae
Radix et Rhizoma Rhei
Pericarpium Cirri Reticulatae
