摘要
目的探讨ICP的口服药物治疗效果,为患者选用经济适用的治疗。方法选取我院2009年1月至2011年6月期间确诊为ICP且在门诊仅接受口服熊去氧胆酸胶囊(优思弗)药物治疗的患者116例,分析这些患者的治疗效果及妊娠结局。结果①终止妊娠的孕周为(36.5±1.5)周。②患者的血清胆红素、肝转氨酶和胆汁酸水平较治疗前明显下降甚至完全恢复正常。差异有统计学意义(P<0.01)。③围生儿结局如早产、羊水粪染、新生儿窒息率等与我院同期正常孕妇的结局相比无差异。结论 ICP患者,在门诊口服熊去氧胆酸治疗有确切疗效。建议选用该方法,既方便病员又能减轻经济负担。
Objective To explore the effect of oral drug treatment for ICP, choose the most affordable treatment for the patients. Methods Select the hospital in January 2009 and June 2011 to the hospital to check and received only oral ursodeoxycholic acid capsules （Ursofalk） therapy in patients with 116 cases of ICP, Analyze the treatment and pregnancy outcomes of these patients. Results （1）Termination of pregnancy gestational age of 36.5±1.5 weeks. （2）Serum bilirubin, liver transaminase and bile acid levels decreased significantly compared with before treatment. Thedifference was statistically significant（P〈 0.01）. Perinatal outcome such as premature,stained amniotic fluid, neonatal asphyxia were no significant difference in pregnancy outcomes with the general hospital pregnants in the same period. Conclusion In the treatment of ICP, there are exact effects in the treatments of oral ursodeoxycholic acid of outpatients It issuggested that we should choose the method, it will bring convenience to the patients and reduce the financial burden at the same time.
出处
《中国医药指南》
2011年第35期271-273,共3页
Guide of China Medicine
关键词
ICP
治疗方法
妊娠结局
ICP
Oral medication
Pregnancy outcomes
