摘要
目的:综述三七皂苷类成分对脑缺血的药理作用和机制研究进展。方法:查阅近年有关文献资料,并进行分析、归纳和总结。结果:三七皂苷类成分对脑血管缺血过程中细胞凋亡、神经元损伤、相关信号通路的蛋白表达等均有明显的影响。结论:三七皂苷类成分对缺血性脑血管疾病的治疗有着广泛的药理基础,其作用机制的研究日益深入,这为三七这一传统中药的进一步开发利用提供了实验依据。
Objective：To summarize the protective effect of sanchinoside on pharmacologic actions and mechanism of cerebral ischemia injury.Method：Consulted the literature of recent five years,to further analyze and summarize.Result：Sanchinoside can obviously affect apoptosis,neurons injuries,protein expression of signal iteral in the process of cerebral ischemia.Conclusion：Sanchinoside have far-reaching basic pharmacological in treat ischemic cerebrovascular disease,and the research of its pharmacologic action and mechanism is increasingly.The article provide experimental evidence on further development of Panax notoginseng.
出处
《辽宁中医药大学学报》
CAS
2011年第10期107-109,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
安徽省中医药管理局中医药科研课题(2009ZY01)
安徽中医学院临床研究基金项目(2009LC1-008A)
关键词
三七皂苷
脑缺血
研究进展
sanchinoside
cerebral ischemia
research progress
