摘要
1例10岁男孩行阑尾切除术过程中用1.5%几丁糖5 mL涂抹在肠管和腹膜表面,以防术后肠粘连。术后患儿胸、腹部出现散在荨麻疹,5 min后荨麻疹遍及全身,并出现面部水肿,呼吸急促,BP 50/30 mm Hg,P 165次/min。考虑过敏性休克与几丁糖有关。立即给予肾上腺素、甲泼尼龙、葡萄糖酸钙等治疗,5 d后患儿痊愈出院。
A 10-year-old boy received topical application of 1.5% chitosan 5 mL on the surfaces of the intestinal tract and peritoneum for preventing postoperative intestinal adhesion during undergoing appendectomy.After surgery,the boy developed urticaria on his chest and abdomen and,5 minutes later,his urticaria progressed to involving his entire body,followed by facial edema,shortness of breath,a BP of 50/30 mm Hg,and a pulse rate of 165 beats/min.Anaphylactic shock was considered to be related to chitosan. Adrenaline,methylprednisolone and calcium gluconate were given immediately and,five days later,the boy recovered and was discharged.
出处
《药物不良反应杂志》
2010年第6期442-443,共2页
Adverse Drug Reactions Journal
