摘要
目的了解临床分离嗜麦芽寡养单胞菌对常用抗菌药物的耐药性,指导临床合理使用抗菌药物。方法使用纸片扩散法测定54株嗜麦芽寡养单胞菌对12种抗菌药物的敏感性。结果嗜麦芽寡养单胞菌对米诺环素的耐药率最低,为3.7%,其次为磺胺甲噁唑/甲氧苄啶(5.6%)和环丙沙星(25.9%),而亚胺培南耐药率为100.0%。结论嗜麦芽寡养单胞菌对米诺环素、磺胺甲噁唑/甲氧苄啶、环丙沙星较敏感,对其他抗菌药物耐药情况严重,临床应加强细菌耐药性的检测和监测。
OBJECTIVE To investigate the resistance of clinical Stenotrophomonas maltophilia isolates to antimicrobial agents.METHODS Susceptibility of 54 S.maltophilia isolates were tested by K-B method.RESULTS The lowest resistance rate of isolates to the antimicrobial agents was to minocycline（3.7%）,then to trimethoprim/sulfamethoxazole（5.6%）and ciprofloxacin（25.9%）.The resistance rate to imipenem was 100.0%.CONCLUSION Most of S.maltophilia isolates are susceptible to minocycline,trimethoprim/sulfamethoxazole and ciprofloxacin and resistant to other antimicrobial agents.It should enhance the monitoring and detection of the clinical bacterial resistance.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第6期1242-1243,共2页
Chinese Journal of Nosocomiology
关键词
嗜麦芽寡养单胞菌
抗菌药物
耐药性
Stenotrophomonas maltophilia
Antimicrobial agents
Resistance
