摘要
目的分析重症监护病房(ICU)非发酵菌感染的临床分布及耐药状况,总结非发酵菌的感染特点,探讨治疗对策。方法采用ATB Expression细菌鉴定及药敏分析系统,对ICU非发酵菌临床分离株进行菌种鉴定及耐药性测定。结果重症监护病房医院感染非发酵菌检出率为45.0%。其中铜绿假单胞菌为最常见(32.1%),其次为鲍氏不动杆菌(27.4%)和嗜麦芽窄食单胞菌(13.3%)。非发酵菌可感染不同部位,其中以呼吸道感染为最常见(75.5%),其次为创面分泌物(8.7%)和引流液(5.5%)。药敏结果显示非发酵菌对替卡西林、庆大霉素、喹诺酮类等多种抗菌药物高度耐药,且多重耐药现象较严重。结论重症监护病房医院感染中非发酵菌分离率高,分布范围广泛且耐药性强,多重耐药现象严重,应引起临床高度重视。
Objective To analyse the antibiotic resistance and clinical distribution of non-fermenters isolated from ICU so as to facilate a further study of clinical treatment. Method Identifications and antibiotic resistanece assays of nonfermenters were done by ATB Expression bacteria analysis system. Results The isolation rate of non-fermenters in ICU was 45.0%. The most common pathogen was Pseudomonas aeruginosa （ 32. 1% ）, the next was Acietobacter baumanii （27.4%） and Pseudomona maltophilia （ 13.3% ）. They could infect any external sites or organ, and be isolated from respiratory tract （75.5%）, secretions of surgical wounds （8.7%） and drawing fluid （5.5%）. These non-fermenters were highly resistant to such antibiotics as teicoplanin gentamycin and quinolones. And cross resistances were very common. Conclusions The isolation rate of non-fermentaters was very high in nosocomial infection in patient of ICU. Non-fermenters can be isolated from a wide varied sources, and its cross resistance to most available antibiotics were rather high. It is very important to pay high clinical attention to those strains for the clinical treatments.
出处
《中国微生态学杂志》
CAS
CSCD
2007年第1期69-71,共3页
Chinese Journal of Microecology
