摘要
目的回顾总结甘油冷冻保存角膜用于穿透性角膜移植(PKP)的临床效果。方法9个新鲜供体眼球分3种方法进行甘油冷冻保存6~349天后,对9例重症角膜患者进行了穿透性角膜移植术,随访6~23个月并记录临床效果。结果全部手术获得成功,77.8%(7/9)的角膜植片获得透明愈合,内皮细胞密度达1400个/mm2。植片混浊的2例患者也得以保存眼球,其中1例更换植片后获得良好视力。结论甘油冷冻保存角膜可能是一种极具前途的角膜活性保存方法。
ObjectiveToreviewtheclinicalresultsofpenetratingkeratoplasty(PKP)usingcryopreservedcorneaswithglycerin. Methods9freshdonoreyeballswerecryopreservedwithglycerinin3differentprocedures.NinepatientswithseriouscornealdiseasesweretreatedbyPKPandwerefollowed-upfor623months.ResultsAllof9operationswereperformedsuccessfully.77.8%(7/9)graftswereclearduringfollow-up,theaverageedothelialcelldensityis1400/mm2.Twograftsof2patientswereopacitybecauseofprimaryfailure,buttheeyeballsweresaved.Oneofthemgotasatisfactoryvisualacuityafterregraftingwithfreshdonorcornea.ConclusionItmaybeanidealmethodforcornealvitalpreservationtocryopreservethedonorcorneawithglycerin.
出处
《眼科研究》
CSCD
1999年第3期202-205,共4页
Chinese Ophthalmic Research
关键词
冷冻保存
甘油
穿透性
角膜移植
cryopreservationglycerinpenetratingkeratoplasty