摘要
目的了解泌尿生殖道支原体属感染状况及耐药性,为临床诊治提供依据。方法对596例泌尿生殖道标本采用法国生物梅里埃公司Mycoplasma IST试剂盒进行支原体属培养、鉴定和药敏试验。结果支原体属培养总阳性率为32.2%,其中解脲脲支原体（Uu）阳性率为28.4%、人支原体（Mh）阳性率为0.3%、Uu＋Mh混合感染阳性率3.5%;Uu对普那霉素、多西环素、交沙霉素、四环素、克拉霉素敏感率为88.8%~95.9%;Uu＋Mh混合感染耐药率较Uu感染耐药率高,其敏感性较高的抗菌药物仅多西环素66.7%和普那霉素76.2%;Uu、Mh对大环内酯类、喹诺酮类耐药率在46.7%~100.0%。结论泌尿生殖道支原体属培养和药敏试验对临床诊断和针对性治疗十分重要。
OBJECTIVE To investigate the infection status and drug resistance of mycoplasma from urogenital tract and provide bases for the clinical treatment.METHODS The mycoplasma cultivation,identification and drug susceptibility testing of 596 specimen collected from urogenital tract were performed by IST2 kit（bioMérieux）.RESULTS The total positive detection rate of mycoplasma was 32.2%.The positive detection rates of ureaplasma urealyicum（Uu）,mycoplasma hominis（Mh） and combination infection were 28.4%,0.3% and 3.5%,respectively.The drug sensitivity rates to pristinamycin,doxycycline,Josamycin,tetracycline and clarithromycin were between 88.8% and 95.9%.The drug resistant rate of combination infection was higher than that of Uu infection.The antibiotics with higher susceptibility were doxycycline（66.7%） and pristinamycine（76.2%）.The drug resistant rates to macrolides and quinolones were between 46.7% and 100.0%.CONCLUSION The mycoplasma cultivation and drug susceptibility testing are important for the clinical diagnosis and treatment.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第3期610-611,共2页
Chinese Journal of Nosocomiology
关键词
泌尿生殖道
支原体属
药敏试验
Urogenital tract
Mycoplasma
Drug susceptibility testing
