摘要
目的调查泌尿生殖道感染解脲脲支原体(Uu)耐药性现状,为临床医师选择抗菌药物提供科学依据。方法采用法国生物梅里埃公司Mycoplasma IST2支原体试剂盒对1347例泌尿生殖道感染患者进行Uu培养和药敏试验。结果 Uu检测阳性率为52.7%,Uu对普那霉素、多西环素、交沙霉素敏感率很高,分别为100.0%、98.3%、96.8%;对红霉素、四环素、阿奇霉素、克拉霉素敏感率较高,为59.5%～92.0%;而对氟喹诺酮类抗菌药物环丙沙星、氧氟沙星敏感率仅11.0%和23.5%。结论目前Uu对氟喹诺酮类抗菌药物耐药率很高,应合理使用抗菌药物,尤其要慎用氟喹诺酮类抗菌药物,才能提高Uu感染的临床治愈率。
OBJECTIVE To investigate the antimicrobial resistance of Ureaplasma urealyticurn （Uu） from infected genitourinary tract and provide the scientific accordance for the clinical application of antibiotics. METHODS The Uu cultivation and drug susceptibility testings were performed for 1347 patients with genitourinary tract infections by bioM6rieux Mycoplasma IST2 kit. RESULTS The total positive detection rate of Uu was 52.7%. The rates of drug sensitivity to pristinamycin （100.0%）, doxycycline （98.3%） and josamycin （96.8M） were higher. Those to erythromycin, tetracycline, azithromycin and clarithromycin were higher, varying from 59.5 % to 92.0%. Those to quinolones such as ciprofloxacin and ofloxacin were 11.0g and 23.5%, respectively. CONCLUSION There is higher resistance rate of quinolones against Uu. It should reasonably use antibiotics, especially for quinolones, in order to improve the cure rate of Uu infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第14期3077-3078,共2页
Chinese Journal of Nosocomiology
关键词
泌尿生殖道
感染
解脲脲支原体
耐药性
Genitourinary tract
Infection
Ureaplasrna urealyticum
Antimicrobial resistance
