摘要
目的探讨经外周动静脉全自动换血法治疗新生儿重度高胆红素血症的方法和疗效。方法对53例符合换血指征的新生儿重度高胆红素患儿,采取外周动静脉同步全自动换血进行治疗;比较换血前后血清胆红素水平(TB)、血糖、电解质及血红蛋白(Hb)、白细胞(WBC)、血小板(PLT)变化。结果换血后总胆红素水平下降,总胆红素换出率为53.12%(P<0.01);Hb、WBC、PLT、K+、Ca2+、Mg2+、pH有所下降;血糖水平升高(P<0.01),但48h内均可恢复正常。换血过程中呼吸、心率、血压、血氧饱和度无明显波动。结论经外周动静脉全自动换血可迅速降低血清胆红素水平,且操作简便、安全,是新生儿换血中较理想的方法。
Objective To study the effect of automated peripheral arteriovenous exchange transfusion for treatment of severe hyperbilirubinemia in neonates.Methods Fifty-three neonates with severe hyperbilirubinemia underwent automated peripheral arteriovenous exchange transfusion,and the changes in the blood gasses,electrolytes and some biochemical indices after the exchange transfusion were evaluated.Results Treatment with the exchange transfusion resulted in a significant reduction in the total serum bilirubin with an exchange rate of 53.12%（P0.01）.The levels of serum kalium,calcium,magnesium,white blood cell count,platelets,and pH showed reductions while blood glucose exhibited a significant elevation changes after the transfusion（P0.01）,which all recovered the normal levels within 48 h.No obvious alterations occurred in the respiration,heart rate,blood pressure,or saturation of blood oxygen during the transfusion.Conclusion Automated peripheral arteriovenous exchange transfusion can rapidly reduce serum bilirubin levels in neonates with severe hyperbilirubinemia without obviously affecting the blood gas balance orblood eletrolyte orglucose levels.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2010年第10期2396-2398,共3页
Journal of Southern Medical University
关键词
新生儿
外周动静脉
高胆红素血症
自动换血法
neonate hyperbilirubinemia peripheral arteriovenous aynchronous automated exchange transfusion
