摘要
目的 研究青光眼患者长期药物治疗的依从性及其影响因素.方法 横断面研究.采用问卷调查与访谈相结合的方式,对门诊长期连续治疗的100例青光眼患者进行调查,了解其药物治疗的依从性及其影响因素.采用SPSS 15.0统计学软件,对影响患者药物治疗依从性的多种因素在X2检验的基础上进行二分类logistic回归分析.结果 100例青光眼患者中,男性54例,女性46例;年龄9～80岁;用药时间从6个月至20年不等.100例中,用药依从者61例（61.0%）,不依从者39例（39.0%）,总体用药依从性为61.0%.调查分析结果表明,患者性别（X2=0.718）、年龄（X2=0.537）、居住地（X2=0.338）、青光眼类型（X2=3.797）、有无手术史（X2=0.338）及医生处方是否征询患者意见（X2=0.297）、是否向患者交待用药方法（X2=0.157）等因素对药物治疗依从性无明显影响,差异无统计学意义（均P〉0.05）.二分类logistic回归分析结果表明,患者用药前眼压（P=0.013）、用药种类（P=0.005）、药液是否滴在眼睑皮肤上（P=0.005）、滴眼液时是否需要帮助（P=0.012）、是否定期复查（P=0.011）、自身对青光眼治疗的信心（P=0.004）等因素对药物治疗依从性有显著影响,差异有统计学意义（均P〈0.05）.患者自述中的药物副作用、滴眼液方案复杂易忘、就医不便（包括候诊时间长）等因素排在影响药物治疗依从性的前3位.结论 临床眼科医师应充分考虑到影响患者药物治疗依从性的多种因素,向患者交代使用抗青光眼药物应注意的问题,给予具体用药指导,以提高青光眼患者的药物治疗依从性,从而增进疗效.
Objective To investigate the medication adherence and modulation factors of medication adherence in long-term treated glaucoma patients. Methods It was a cross-sectional study.One hundred glaucoma patients who have been followed-up for more than 6 month in the Second Hospital affiliated to Medical College of Zhejiang University were investigated with questionnaires and interview.The data was analyzed by binary logistic regression and X2 test.Results In the 100 glaucoma patients being ivestigated,the medication compliance of patients is 61（61.0%）,the medication non-compliance of patients is 39（39.0%）.Age,gender,habitat,glaucoma types,surgical history,inquesting patient before writing out a prescription and informing them the methods for application of eyedrops were not significantly co-related with medication adherence（X2=0.718,0.537,0.338,3.797,0.338,0.297,0.157;P〉0.05）.Intraocular pressure before treatment,types of eyedrops,instillation of eye-drops to the eyelids,request for help during application of eyedrops,rechecking regularly and confidence in glaucoma treatment were found significantly related to medication adherence（P=0.013,0.005,0.005,0.012,0.011,0.004）.However,drug side effect,forgetting application of eyedrops and inconvenience to see a doctor was considered the most important factors by patients in the interview.Conclusions Glaucoma physicians should discuss with patients about the methods for the application of glaucoma medication.This can improve the medication adherence of glaucoma patients and promote the therapeutic effect.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2010年第6期494-498,共5页
Chinese Journal of Ophthalmology
关键词
青光眼
药物疗法
病人依从
横断面研究
Glaucoma
Drug therapy
Patient compliance
Cross-sectional studies
